MétaCan
Menu
← Back to cohort

Twenty-one days of bed rest alter motor unit properties and neuromuscular junction transmission in young adults

2025· article· en· W4410313237 on OpenAlexaff
Fabio Sarto, Miloš Kalc, Evgeniia Motanova, Martino V. Franchi, Daniel W. Stashuk, Nina Murks, Giacomo Valli, Samuele Negro, Tomaž Prašnikar, Mladen Gasparini, Giovanni Martino, Giuseppe De Vito, Aleš Holobar, Boštjan Šimunič, Rado Pišot, Marco Narici

Bibliographic record

VenueJournal of Applied Physiology · 2025
Typearticle
Languageen
FieldEngineering
TopicMuscle activation and electromyography studies
Canadian institutionsUniversity of Waterloo
FundersNextGenerationEUJavna Agencija za Raziskovalno Dejavnost RSHORIZON EUROPE Marie Sklodowska-Curie ActionsAgenzia Spaziale ItalianaMinistero dell’Istruzione, dell’Università e della Ricerca
KeywordsMotor unitNeuromuscular junctionElectromyographyNeuromuscular transmissionMotor unit recruitmentDenervationInternal medicineMedicineContraction (grammar)CardiologyAnatomyBiologyPhysical medicine and rehabilitationNeuroscience

Abstract

fetched live from OpenAlex

Leveraging both intramuscular and high-density surface EMG recordings in the vastus lateralis, we identified alterations in motor unit (MU) properties in young adults after 21 days of bed rest. These included reduced discharge rates and changes in MU potential size and complexity, observed at both low and moderate contraction intensities. Evidence of impaired neuromuscular junction (NMJ) function and denervation was also found. Our findings indicate that medium-term disuse elicits MU-level changes not detected in shorter-duration studies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.199
Teacher spread0.188 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueJournal of Applied Physiology→Same topicMuscle activation and electromyography studies→French-language works237,207→