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Record W4410314324 · doi:10.1093/eurjpc/zwaf286

New diagnosis of diabetes in patients with myocardial infarction or stroke: a systematic review and meta-analysis

2025· review· en· W4410314324 on OpenAlexafffund
Marwa Douelrachad, Alexander Thistle, Hibo Rijal, Ari Ochuba, Calvin Ke, Charlotte Lee, Manav V. Vyas

Bibliographic record

VenueEuropean Journal of Preventive Cardiology · 2025
Typereview
Languageen
FieldMedicine
TopicDiabetes, Cardiovascular Risks, and Lipoproteins
Canadian institutionsToronto Metropolitan UniversityToronto General HospitalUniversity of TorontoUniversity Health NetworkSt. Michael's HospitalWestern UniversityQueen's UniversityThe Scarborough HospitalYork University
FundersHeart and Stroke Foundation of Canada
KeywordsMedicineDiabetes mellitusStroke (engine)Meta-analysisChecklistConfidence intervalMyocardial infarctionInternal medicineMEDLINEObservational study

Abstract

fetched live from OpenAlex

AIMS: What proportion of patients with an acute myocardial infarction (MI) or stroke get a new diagnosis of diabetes (NDD) at the time of hospitalization is unclear. METHODS AND RESULTS: We systematically searched MEDLINE and Embase from database inception to 30 January 2025, to select English-language observational studies that included adult patients with MI or stroke and reported the number of patients with NDD. The denominator was patients without known diabetes. Study quality was assessed using the Joanna Briggs Institute checklist. Random-effects meta-analyses were used to calculate the pooled proportion of NDD in patients with MI or stroke. Heterogeneity was explored in subgroup analyses, and any change over time was evaluated using meta-regression. 82 studies that included 9440 patients with NDD were identified. Included studies were of good methodological quality: 17 (22%) tested all eligible patients for diabetes, and 19 (23%) used registry-based samples. 16.0% [95% confidence interval (CI), 14.3-17.7, n = 52] patients with MI had NDD, and 15.3% (95% CI 12.5-18.0, n = 30) patients with stroke had NDD, albeit with high heterogeneity. The pooled proportion was higher when oral glucose tolerance test was used to diagnose diabetes. The proportion of NDD did not change over the last 30 years (0.1% per year decline; 95% CI -0.3% to 0.1%). CONCLUSION: Among patients admitted with MI or stroke, one in six gets a new diagnosis of diabetes. Improving diabetes screening could help identify people before having a diabetes-related cardiovascular event.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Meta-epidemiology (broad)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.337
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0180.008
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.286
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

Explore more

Same venueEuropean Journal of Preventive CardiologySame topicDiabetes, Cardiovascular Risks, and LipoproteinsFrench-language works237,207