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Record W4410319169 · doi:10.15557/pipk.2024.0045

Treatment of menopausal vasomotor symptoms and sensory issues in a 53-year-old autistic woman – a case report

2025· article· en· W4410319169 on OpenAlexaff
Agnieszka Rynkiewicz, Ewa Ferensztajn‐Rochowiak, Rachel Moseley, Julie M. Turner‐Cobb, Nouchine Hadjikhani, Adeline Lacroix, Alicia Brewer Curran, Kristin Sohl, Dorota Darmochwał-Kolarz

Bibliographic record

VenuePsychiatria i Psychologia Kliniczna · 2025
Typearticle
Languageen
FieldNeuroscience
TopicAutism Spectrum Disorder Research
Canadian institutionsCentre for Addiction and Mental Health
Fundersnot available
KeywordsVasomotorMedicinePsychologyAudiologyPsychiatryAnesthesia

Abstract

fetched live from OpenAlex

Considered a taboo topic in many societies, menopause in autistic women is still under-recognised, and little research addresses its impact. Existing studies suggest that this often-difficult transition period is associated with numerous unmet health needs and a frustrating lack of knowledge and support from healthcare professionals. Menopausal vasomotor symptoms, the hallmark of menopause, can intensify and worsen sensory sensitivities in many autistic women. We present the case of a 53-year-old Caucasian autistic woman without intellectual disability or other current psychiatric comorbidities. The patient underwent gynaecologic and hormonal lab testing, and was introduced to hormone replacement therapy to ameliorate symptoms of oestradiol and progesterone deficiency. Menopausal vasomotor symptoms experienced by the patient were monitored over a period of seven months following the implementation of hormone replacement therapy and non-pharmacologic approaches. Hormone replacement therapy decreased menopausal vasomotor symptoms, but not all her initial complains. Strong sensory issues were linked to more severe menopausal vasomotor symptoms. This case highlights the need for further research and the development of the global Extension for Community Health Outcomes (ECHO) Autism® model to advance medical care offered to autistic women during menopause.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.069
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.386
Teacher spread0.348 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

Explore more

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