Pain management of hip osteoarthritis with corticosteroids vs injection therapies: a systematic review and meta-analysis
Bibliographic record
Abstract
INTRODUCTION: Osteoarthritis (OA) is the most common degenerative joint disease, characterized by chronic pain and articular cartilage damage. Hip OA is characterized by the progressive breakdown of articular cartilage within the hip, particularly the hip joints ball and socket structure, Hip OA leads to joint pain, stiffness and causes functional limitations. AIM: To analyse the effectiveness of intra-articular corticosteroids (IA CS) use against other injection therapies for the symptomatic management of hip OA. METHODS: PROSPERO registered-CRD42024526221. Medline, Embase, Scopus and Web of Science were searched for trials. INCLUSION CRITERIA: Adults with symptomatic hip OA, randomised trials for treatment of hip OA with IA injection methods. Studies must involve comparators and the outcome measure must include a measurement of pain such as Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) or the visual analogue scale (VAS). Cochrane risk of bias and JBI critical appraisal tools assessed risk of bias. RevMan was used for creation of statistical figures within the meta-analysis. RESULTS: Data extracted in the systematic review presented improvements on pain, function, stiffness, and overall scores using WOMAC and VAS scales. However, data from the meta-analysis indicates that there is no statistical significance (significance is a p value < 0.05) between corticosteroids and placebo or hyaluronic acid (HA). Meta-analyses produced p values of 0.05 when comparing CS and placebo WOMAC pain scores at 2 months, CS and HA overall WOMAC at 6 months-p value of 0.46. WOMAC stiffness and function scores between CS and placebo at 2 months-p value of 0.05 and 0.08, thus statistically insignificant. CONCLUSION: This meta-analysis shows that IA corticosteroid injections for hip OA don't provide statistically significant symptomatic improvement for patients compared to placebo. Showing the urgent need to assess other therapies in hip OA treatment.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.012 | 0.024 |
| Meta-epidemiology (narrow) | 0.003 | 0.001 |
| Meta-epidemiology (broad) | 0.023 | 0.034 |
| Bibliometrics | 0.006 | 0.006 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.003 | 0.002 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.002 | 0.002 |
| Insufficient payload (model declined to judge) | 0.004 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".