MétaCan
Menu
← Back to cohort
Record W4410426026 · doi:10.1101/2025.05.15.25326936

Childhood Maltreatment and Mental-Physical Multimorbidity: An Analysis of Canadian Survey Data Using Entropy Balancing

2025· preprint· en· W4410426026 on OpenAlexaffabout
Andrew J Fullerton, Alpamys Issanov, Rafael Meza

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldSocial Sciences
TopicHealth disparities and outcomes
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMultimorbidityPsychologyEntropy (arrow of time)PsychiatryComorbidityPhysics

Abstract

fetched live from OpenAlex

ABSTRACT Objectives To explore childhood maltreatment as a risk factor for mental-physical multimorbidity and examine gender as an effect modifier. Methods We analyzed data from the 2022 Mental Health and Access to Care Survey. We described sample characteristics with unweighted counts, survey-weighted percentages, and weighted chi-square tests. Missing data were addressed via multiple imputation. Entropy balancing adjusted for age, gender, LGBTQ2+ identity, visible minority group, and immigration status and multinomial logistic regression was used to estimate associations between the number of childhood maltreatment subtypes (physical abuse, sexual abuse, and exposure to domestic violence) reported and physical (≥ 2 physical conditions but no mental), mental (≥ 2 mental conditions but no physical), and mental-physical (≥ 1 mental and physical condition) multimorbidity. Survey weights were applied during both entropy balancing and regression modeling. Effect modification by gender was examined and sub-analyses of mental- cardiometabolic, mental-inflammatory, mental-somatic multimorbidity, and subtype-specific exposures were conducted. Results 8,967 respondents were included. Mental-physical multimorbidity increased with maltreatment: 3.4% (none, n=4647), 6.3% (1 type, n=2804), 10.1% (2 types, n=1208), and 18.2% (3 types, n=308). Adjusted odds ratios for mental-physical multimorbidity ranged from 2.15 (95% CI:1.90-2.44) for 1 type to 8.72 (95% CI:7.01-10.85) for 3 types compared to physical (aOR=1.31-2.00) and mental (aOR=1.90-3.63) multimorbidity. Men showed higher odds of mental-physical multimorbidity at high exposure (aOR=6.14, 95% CI:4.90-7.70 in women; aOR=13.96, 95% CI:9.58-20.34 in men) with varying effect sizes across disease areas. Conclusion Childhood maltreatment shows a strong dose-response association with mental- physical multimorbidity. Further research is needed to clarify gender-specific pathways.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.022
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.019
Threshold uncertainty score0.140

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.022
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.003
Bibliometrics0.0060.016
Science and technology studies0.0020.001
Scholarly communication0.0020.001
Open science0.0020.002
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.107
GPT teacher head0.395
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

Explore more

Same venuemedRxiv→Same topicHealth disparities and outcomes→French-language works237,207→