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LIVING WITH SYSTEMIC LUPUS ERYTHEMATOSUS IN MAURITIUS: A NARRATIVE STUDY OF PATIENT EXPERIENCES

2025· article· en· W4410513165 on OpenAlexvenueno aff
Dalilah Kalla

Bibliographic record

VenueThe Journal of Rheumatology · 2025
Typearticle
Languageen
FieldMedicine
TopicSystemic Lupus Erythematosus Research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineNarrativeSystemic diseaseDermatologyLupus erythematosusImmunopathologyImmunologyAntibodyLiterature

Abstract

fetched live from OpenAlex

PV176 / #700 Poster Topic: AS19 - Patient-Reported Outcome Measures Background/Purpose Systemic Lupus Erythematosus (SLE), commonly known as Lupus, is a complex, chronic autoimmune disease characterized by the immune system attacking healthy tissue and organs. The condition presents a broad spectrum of physical, psychological, and social challenges, significantly affecting patients’ quality of life. While advances in clinical research have improved diagnostic and therapeutic strategies, the personal and social dimensions of living with SLE remain underexplored, particularly in regions such as Mauritius where public awareness and systemic support may be limited. This study aimed to investigate the lived experiences of individuals diagnosed with SLE in Mauritius, focusing on their emotional, social, and practical challenges. Methods Employing a narrative methodology, data were collected through in-depth telephone interviews with 60 participants diagnosed with SLE. The interviews were designed to capture rich qualitative data on sociodemographic characteristics and personal reflections using open-ended questions. Participants represented diverse backgrounds, ensuring a comprehensive exploration of experiences. The analysis involved meticulous transcription, iterative reading, and thematic coding. The data were structured around 3 key domains informed by both existing literature and study findings: Pre-Diagnosis: Participants described the prolonged diagnostic journeys marked by misdiagnosis, lack of awareness, and frustration with the healthcare system. Response to Diagnosis: While receiving a diagnosis brought relief and validation of symptoms, it also elicited fear, denial, and anxiety about managing a lifelong condition. Daily Challenges and Coping Mechanisms: Six overarching themes emerged from these domains: Pain and Fatigue: The pervasive physical symptoms disrupted daily routines and social engagement. Changes in Appearance: Visible manifestations such as skin rashes and hair loss impacted participants’ self-esteem and social confidence. Impact on Relationships: Strain on familial, social, and professional relationships was widely reported, with many citing stigma and lack of understanding from others. Emotional Burden: Participants experienced fear of disease progression, frustration with medical uncertainty, and struggles with mental health. Economic Strain: The financial burden of lifelong treatment, frequent medical visits, and reduced work capacity added significant stress. Support Networks: Many participants emphasized the absence of sufficient emotional and practical support from family, employers, and even healthcare providers. Results The findings underscore the multifaceted impact of SLE on patients’ lives, highlighting systemic gaps in awareness, early diagnosis, and support mechanisms. Participants called for enhanced public education about SLE, greater sensitivity from employers and medical professionals, and the establishment of community-based support groups. Conclusions This study contributes to the growing body of research on chronic illness in underrepresented populations, emphasizing the need for tailored interventions in Mauritius and across the African continent. Enhanced public health initiatives and patient-centered care models are crucial to addressing the unmet needs of individuals with SLE, fostering greater inclusion, and improving their quality of life.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.033

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.011
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.002
Science and technology studies0.0080.006
Scholarly communication0.0040.004
Open science0.0010.006
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.291
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2025
Admission routes1
Has abstractyes

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