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Record W4410523770 · doi:10.1136/bmjoq-2025-qshu.19

19 Prehabilitation in open gynecologic oncology procedures and radical cystectomy: a pathway to better outcomes and cost savings

2025· article· en· W4410523770 on OpenAlexaff
Timothy Frewin, Holly Edmond, Kelly Mayson

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicCancer survivorship and care
Canadian institutionsVancouver Coastal HealthUniversity of British Columbia
Fundersnot available
KeywordsPrehabilitationGynecologic oncologyCystectomyMedicineOncologyInternal medicineBladder cancerCancerPhysiology

Abstract

fetched live from OpenAlex

Introduction As the surgical population ages, the risk of post-operative complications rises, highlighting the need for effective reduction strategies. Prehabilitation, a multimodal optimization program, seeks to reduce post-operative complications and enhance patient satisfaction. However, its cost-effectiveness and optimal implementation strategies remain unclear.Methods This study evaluated patients undergoing major gynecologic-oncology (N = 154) and radical cystectomy procedures (N = 62) at Vancouver General Hospital (VGH) in British Columbia, Canada, from 2017–2020. The prehabilitation in this study is part of the Surgical Patient Optimization Collaborative (SPOC), which promotes preoperative optimization across British Columbia. Our site selected seven of the 13 potential clinical components for preoptimization: smoking, anemia, diabetes, sleep apnea, nutrition, pain, and cardiovascular disease. Patients were identified preoperatively through surgical screening questionaries and promptly referred to management or treatment programs. Cost analysis used NSQIP and CIHI data, comparing prehabilitation patients to a matched control group while accounting for implementation costs (SPOC).Results Prehabilitation reduced costs by $480 per gynecologic-oncology patient, primarily by lowering readmissions and reoperations. For radical cystectomy, savings were $5,626 per patient, largely from reduced same-stay complications. Implementation prehabilitation costs for this study were estimated at $250, due to pre-existing programs. Assuming an optimization rate of 75%, annual net savings at VGH are estimated at $43,054 for gynecologic oncology and $342,741 for radical cystectomy procedures. Additionally, 75% of patients reported improved surgical experiences.Conclusion Prehabilitation enhances patient experience, reduces complications, and provides substantial cost savings, supporting its integration into surgical care pathways. These findings underscore its potential for broader adoption in preoperative optimization efforts.References Barberan-Garcia A, Ubre M, Pascual-Argente N, et al. Post-discharge impact and cost-consequence analysis of prehabilitation in high-risk patients undergoing major abdominal surgery: secondary results from a randomised controlled trial. British Journal of Anaesthesia 2019;123(4):450–456.Gillis C, Ljungqvist O, Carli F. Prehabilitation, enhanced recovery after surgery, or both? A narrative review. British Journal of Anaesthesia 2022;128(3).McIsaac DI, Gill M, Boland L, et al. Prehabilitation in adult patients undergoing surgery: an umbrella review of systematic reviews. British Journal of Anaesthesia 2022;128(2):244–257.Metzner M, Mayson K, Schierbeck G, Wallace T. The implementation of preoperative optimization in British Columbia: a quality improvement initiative. Can J Anaesth. 2024;71(12):1672–1684.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.040

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.001
Science and technology studies0.0010.000
Scholarly communication0.0030.001
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0120.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.346
Teacher spread0.329 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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