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The ethylene responsive factor TaERF-2 A activates gibberellin 2-oxidase gene TaGA2ox2-3B expression to enhance seed dormancy in wheat

2025· article· en· W4410544681 on OpenAlexaff
Wei Gao, Renjie Wang, Yanan Yan, Xinyi Xu, Chuanxi Ma, Haiping Zhang, Cheng Chang

Bibliographic record

VenueInternational Journal of Biological Macromolecules · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicSeed Germination and Physiology
Canadian institutionsMinistry of Agriculture
FundersJiangsu Collaborative Innovation Center for Modern Crop ProductionNational Natural Science Foundation of China
KeywordsGibberellinDormancyEthyleneGene expressionGerminationChemistryCell biologyGeneBotanyHorticultureBiologyBiochemistry

Abstract

fetched live from OpenAlex

The plant hormone gibberellin (GA) plays a key role in breaking seed dormancy, but the underlying regulatory mechanism is not fully understood. Here, we reported TraesCS3B02G166100 (named TaGA2ox2-3B ), encoding a GA metabolism enzyme GA2ox family member, to be differentially expressed in strong- and weak-dormancy wheat seeds during germination. We confirmed that the ERF transcription factor TaERF-2 A directly bound to the TaGA2ox2-3B promoter and enhanced its transcription. Germination tests indicated that TaERF-2 A positively regulated seed dormancy in wheat. Additionally, 12 mutations were identified within the promoter and coding regions of TaGA2ox2-3B when comparing strong- and weak-dormancy wheat varieties. Six molecular markers were developed to verify correlations between these mutations and seed dormancy. Transgenic experiments verified the potential of the TaGA2ox2-3B +2246-A allele to enhance seed dormancy. Physiological and biochemical analyses indicated that the TaERF-2 A-TaGA2ox2-3B module modulated seed dormancy by influencing GA metabolism and signaling pathways. Collectively, this study revealed the molecular mechanism of GA regulating seed dormancy, and identified genetic resources and molecular markers to breed wheat varieties with preharvest sprouting resistance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.002

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.300
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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