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Record W4410593836 · doi:10.1016/j.clcb.2025.100152

Towards cellular agriculture: An exploratory supply chain model

2025· article· en· W4410593836 on OpenAlexafffund
Dawne M. Skinner, John T. Blake, Claver Diallo

Bibliographic record

VenueCleaner and Circular Bioeconomy · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicFood Waste Reduction and Sustainability
Canadian institutionsDalhousie University
FundersResearch Nova ScotiaMitacs
KeywordsSupply chainAgricultureBusinessIndustrial organizationExploratory researchAgricultural economicsEconomicsMarketingGeographySociology

Abstract

fetched live from OpenAlex

Cellular agriculture, which uses biotechnology to produce animal-derived products, has been identified as a possible solution to reduce the negative environmental impacts associated with traditional meat and dairy production. However, available life cycle and techno-economic assessments for cultured meat production suggest that additional environmental and cost improvements are needed to compete with traditional meat production methods. The adoption of circular supply chains has been found to improve the economic and environmental outcomes of production processes. The use of agricultural and food byproducts, such as hydrolyzed soymeal, as a source of amino acids has been identified as a way to reduce cost and environmental impacts. However, the impact of these undefined sources on cell production efficiency is largely unknown. The aim of this paper is to develop a novel exploratory supply chain model for a viable large-scale cellular agriculture network that considers facility location, ingredient blending, capacity design and technology selection problems. A bi-objective mixed integer linear programming model is developed to investigate the dynamics between demand, capacity design, location, ingredient blending and technology selection decisions as well as trade offs when optimizing for cost versus carbon emissions. Useful managerial insights are developed through various computational experiments, including modeling supply chain network design under deterministic and stochastic demand and the development of iso-cost curves to help decision makers design the optimal blending of chemically undefined byproduct ingredients with pure pharmaceutically sourced ingredients. • Cellular agriculture makes meat and dairy products via biotechnological processes. • Cell Ag has potential to reduce the environmental impact of meat/dairy production. • An exploratory supply chain model for a large-scale Cell Ag network is developed. • Addresses location–allocation, blending, capacity, tech selection/sizing decisions. • Dynamics and trade-offs of design factors, costs and carbon emissions are studied.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.787
Threshold uncertainty score0.287

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.212
Teacher spread0.199 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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