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Record W4410606036 · doi:10.1101/2025.05.20.655058

Perturbing postural stability during treadmill walking with dysfunctional electrical stimulation

2025· preprint· en· W4410606036 on OpenAlexafffund
Tomoko Miyata, Naoto Izumi, K Kimura, Takeshi Yamaguchi, Shin-ichiroh Yamamoto, Kei Masani

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldEngineering
TopicMuscle activation and electromyography studies
Canadian institutionsToronto Rehabilitation InstituteUniversity of Toronto
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsDysfunctional familyFunctional electrical stimulationPhysical medicine and rehabilitationStimulationTreadmillStability (learning theory)PsychologyPhysical therapyMedicineComputer scienceNeurosciencePsychotherapist

Abstract

fetched live from OpenAlex

Abstract Functional electrical stimulation is commonly used to enhance human movement through low-level electrical activation of muscles. More recently, dysfunctional electrical stimulation (DFES) has been proposed as a method to perturb gait by artificially inducing discomfort and mimicking inadequate muscle activity. Here we investigated strategies to induce internal perturbations during treadmill walking using DFES by systematically varying the timing and target muscle. Eleven healthy participants walked at three different speeds while DFES was applied to the tibialis anterior (TA), soleus (SOL), rectus femoris (RF), and biceps femoris (BF) muscles at 25%, 50%, 75%, and 100% of the gait cycle, each for a duration of 0.2 seconds. The gait cycle was time-locked to heel contact (0%). Results showed a significant reduction in the anterior-posterior margin of stability compared to baseline, particularly when DFES was applied to the SOL at 75%, the RF at 50%, and the BF at 75% of the gait cycle. Under these conditions, increased knee flexion and shorter stride intervals were observed relative to baseline. In conclusion, we identified effective DFES conditions to induce postural instability during walking. By mimicking inadequate muscle activity, DFES provides a promising method to study dynamic balance control and mechanisms underlying falls in neurological populations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.002

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.193
Teacher spread0.183 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

Explore more

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