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Record W4410622661 · doi:10.48305/arya.2025.42469.2938

Comparing the power of obesity indices to predict cardiovascular diseases at different ages: An application of conditional time-dependent ROC curve in Healthy Heart Cohort of Yazd, Iran.

2025· article· en· W4410622661 on OpenAlexaff
Mohammad Hashem Khademi Kolah Loui, Sara Jambarsang, Seyedeh Mahideh Namayandeh, Seyyed Mohammad Tabatabaei, Abdollah Hozhabrnia, Reyhane Sefidkar

Bibliographic record

VenuePubMed · 2025
Typearticle
Languageen
FieldMedicine
TopicDiabetes, Cardiovascular Risks, and Lipoproteins
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsMedicineCohortObesityReceiver operating characteristicInternal medicineCardiologyDemography

Abstract

fetched live from OpenAlex

BACKGROUND: This study was conducted to estimate the power of anthropometric markers to predict 10-year CVD across different age groups in the Yazd Healthy Heart cohort. METHODS: A total of 1,623 individuals aged 20 to 74, who were free of CVD, participated in the study. A conditional time-dependent receiver operating characteristic (ROC) curve was used to estimate the predictive power of anthropometric indices, including the Abdominal Volume Index (AVI), Body Adiposity Index (BAI), and Waist-to-Height Ratio (WHtR), adjusted for age and sex. RESULTS: Of the 1,623 participants, 818 were males (50.40%) and 805 were females (49.60%). The Area Under the Curve (AUC) for the BAI ranged from 0.50 to 0.70 for males aged 40 to 70 years. In females, the BAI biomarker demonstrated considerable to excellent predictive power (AUC > 0.8) for individuals aged 20 to approximately 33 years. For males, AVI and WHtR showed fair to considerable predictive power in participants aged 20 to 30 years. In the age group of 30 to approximately 68 years, the predictive power varied from poor to ineffective, except for individuals close to 50 years old. In females, the predictive power of the AVI and WHtR biomarkers ranged from fair to considerable for those aged 20 to around 33 years. CONCLUSION: This study found that AVI and WHtR can fairly predict 10-year CVD risk in young individuals of both sexes, while the BAI was specifically applicable for predicting risk in young women. These markers are valuable and affordable tools for youth CVD screening.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.016
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.050

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.016
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.238
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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