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Record W4410738075 · doi:10.1109/tbme.2025.3573581

ECG-SMART-NET: A Deep Learning Architecture for Precise ECG Diagnosis of Occlusion Myocardial Infarction

2025· article· en· W4410738075 on OpenAlexaff
Nathan T. Riek, Murat Akçakaya, Zeineb Bouzid, Stephanie Helman, Karina Kraevsky-Philips, Rui Qi Ji, Ervin Sejdić, Jessica K. Zègre‐Hemsey, Christian Martin‐Gill, Clifton W. Callaway, Samir Saba, Salah S. Al‐Zaiti

Bibliographic record

VenueIEEE Transactions on Biomedical Engineering · 2025
Typearticle
Languageen
FieldMedicine
TopicECG Monitoring and Analysis
Canadian institutionsUniversity of Toronto
FundersNational Center for Advancing Translational SciencesNational Institute of Nursing ResearchNational Heart, Lung, and Blood InstituteNational Institutes of Health
KeywordsMyocardial infarctionCardiologyElectrocardiographyInternal medicineComputer scienceOcclusionMedicineBiomedical engineeringArtificial intelligence

Abstract

fetched live from OpenAlex

OBJECTIVE: In this paper we develop and evaluate ECG-SMART-NET for occlusion myocardial infarction (OMI) identification. OMI is a severe form of heart attack characterized by complete blockage of one or more coronary arteries requiring immediate referral for cardiac catheterization to restore blood flow to the heart. Two thirds of OMI cases are difficult to visually identify from a 12-lead electrocardiogram (ECG) and can be potentially fatal if not identified quickly. Previous works on this topic are scarce, and current state-of-the-art evidence suggests both feature-based random forests and convolutional neural networks (CNNs) are promising approaches to improve ECG detection of OMI. METHODS: While the ResNet architecture has been adapted for use with ECG recordings, it is not ideally suited to capture informative temporal features within each lead and the spatial concordance or discordance across leads. We propose a clinically informed modification of the ResNet-18 architecture. The model first learns temporal features through temporal convolutional layers with 1xk kernels followed by a spatial convolutional layer, after the residual blocks, with 12x1 kernels to learn spatial features. RESULTS: ECG-SMART-NET was benchmarked against the original ResNet-18 and other state-of-the-art models on a multisite real-word clinical dataset that consists of 10, 393 ECGs from 7, 397 unique patients (rate of OMI = 7.2%). ECG-SMART-NET outperformed other models in the classification of OMI with a test AUC of 0.953 [0.921, 0.978]. CONCLUSION AND SIGNIFICANCE: ECG-SMART-NET can outperform the state-of-the-art random forest for OMI prediction and is better suited for this task than the original ResNet-18 architecture.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.245
Teacher spread0.239 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2025
Admission routes1
Has abstractyes

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