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Exploring treatment adherence and unmet needs of older breast cancer survival in Nigeria.

2025· article· en· W4410795585 on OpenAlexaff
Nanre Nden Makama Mampak, Margaret I. Fitch, Runcie C.W. Chidebe, Kenai A Nanchak

Bibliographic record

VenueJournal of Clinical Oncology · 2025
Typearticle
Languageen
FieldMedicine
TopicGlobal Cancer Incidence and Screening
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsMedicineBreast cancerOncologyCancerGerontologyFamily medicineInternal medicine

Abstract

fetched live from OpenAlex

e13849 Background: Breast cancer is the leading cause of cancer death in Nigeria. Older breast cancer patients often experience additional vulnerabilities due to comorbidities, reduced physical resilience, and potential socio-economic limitations that impact their access to chemotherapy, radiotherapy, and targeted therapy. Yet the needs of older breast cancer patients have remained unknown in Nigeria. Hence, this study explored the relationship between unmet needs and treatment adherence among older adults with breast cancer undergoing chemotherapy at a cancer facility in Nigeria. Methods: The participants were (n = 66) people aged 55 to 74 who were undergoing chemotherapy. Data were collected using structured questionnaires and analyzed using descriptive statistics and chi-square tests. Results: The majority were married (53%), and more than half were unemployed (54.5%). Nearly half of the respondents (47%) had an income of less than ₦500,000 per year. In terms of cancer stages, 45.5% of participants were at stage 3, indicating a high prevalence of advanced cancer. The analysis showed that 74.2% of participants reported unmet needs. A significant relationship between unmet needs and treatment compliance was found (χ² = 4.580, p = 0.032). Participants with unmet needs were less likely to exhibit good compliance (77.6%) compared to those whose needs were met (100%). Conclusions: The study highlights the substantial unmet needs among older breast cancer patients, which significantly affect treatment adherence. To enhance treatment adherence and overall quality of life, it is recommended that healthcare providers and policymakers develop targeted interventions to address the specific unmet needs of older cancer patients. This includes improving access to comprehensive care, implementing ASCO practical geriatric assessment, providing socio-economic support, and implementing strategies to manage comorbidities effectively in Nigeria. Key Words: Brest Cancer, Chemotherapy, Older Adults, Unmet Needs, Health Care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.458
GPT teacher head0.531
Teacher spread0.073 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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