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Record W4410800742 · doi:10.1101/2025.05.23.655831

Unravelling neuromechanical constraints to finger independence

2025· preprint· en· W4410800742 on OpenAlexafffund
Daanish M. Mulla, Paul M Tilley, Peter J. Keir

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldEngineering
TopicMuscle activation and electromyography studies
Canadian institutionsWestern UniversityMcMaster UniversityYork University
FundersNatural Sciences and Engineering Research Council of CanadaMcMaster University
KeywordsIndependence (probability theory)Computer scienceMathematics

Abstract

fetched live from OpenAlex

Abstract Intentional use of a single finger results in involuntary forces and movements among other fingers. Constraints to finger independence are attributed to both neural and mechanical factors, but the contribution of these factors is debated. We hypothesized that neural factors primarily constrain finger independence during isometric exertions whereas mechanical factors impose larger constraints during movements. We investigated changes in finger independence following a ring finger fatigue protocol. We assumed that with fatigue, the ability to actively transmit forces across fingers through neural pathways will be reduced but force transmission passively through mechanical pathways will remain unaffected. Participants performed isometric finger contractions and flexion-extension movements at baseline and following a ring finger fatigue protocol. At baseline, involuntary ring finger forces ranged from 7.3-16.5% MVC. Consistent with our predictions, involuntary ring finger forces decreased by 2.5-8.9% MVC following fatigue. In contrast, involuntary ring finger movement did not change or surprisingly in several cases, increased by greater than 10-20° following fatigue relative to baseline across movement tasks. Our findings demonstrate that the neuromechanical control of finger force versus motion are distinct from each other and can alter the constraints to finger independence in a task-dependent way.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.214
Teacher spread0.201 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

Explore more

Same venuebioRxiv (Cold Spring Harbor Laboratory)→Same topicMuscle activation and electromyography studies→French-language works237,207→