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Record W4410820178 · doi:10.1097/wad.0000000000000675

Correlation of Depression and Anxiety Responses on the Mild Behavioral Impairment Checklist With the Cornell Scale for Depression in Dementia and Abbreviated Version of the Penn State Worry Questionnaire

2025· article· en· W4410820178 on OpenAlexaff
Aditya Aundhakar, Fahad Rajput, Aravind Ganesh, Zahinoor Ismail, Eric E. Smith

Bibliographic record

VenueAlzheimer Disease & Associated Disorders · 2025
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsHotchkiss Brain InstituteUniversity of Calgary
Fundersnot available
KeywordsAnxietyWorryMoodPsychologyDepression (economics)DementiaApathyPsychiatryClinical psychologyChecklistGeriatric Depression ScaleCognitionMedicineDepressive symptomsInternal medicine

Abstract

fetched live from OpenAlex

INTRODUCTION: Cognitive disorders are often accompanied by depression and anxiety. The Mild Behavioral Impairment Checklist (MBI-C) was developed to capture neuropsychiatric symptoms that predict risk for dementia and includes questions on mood, but has not been validated for identifying significant depression or anxiety symptoms. Our objective was to determine whether MBI-C mood domain scores predict responses on 2 previously validated scales: the Cornell Scale for Depression in Dementia (CSDD) and the Penn State Worry Questionnaire-Abbreviated version (PSWQ-A) scales. METHODS: We performed a cross-sectional analysis of consenting patients from a memory clinic who completed the MBI-C along with the CSDD (n=80) or PSWQ-A (n=92). RESULTS: MBI-C mood scores and the MBI-C depression subscore were moderately to strongly correlated with the CSDD (r=0.72) and the PSWQ-A (r=0.66). An MBI-C mood score of ≥5 or anxiety or depression subscore ≥2 predicted clinically relevant depressive and anxiety symptoms on the CSDD and PSWQ, respectively, with AUCs between 0.80 and 0.85. CONCLUSIONS: This study supports the MBI-C mood score as a valid tool for screening for mood-related neuropsychiatric symptoms in individuals with cognitive impairment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.336

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.283
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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