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Record W4410829091 · doi:10.18502/jirb.v13i1.18766

Polycystic Ovary Syndrome Herbal Treatments and Medicinal Plants: A Comprehensive Review

2025· review· en· W4410829091 on OpenAlexaff
Kimia Goudarzi, Jahangir Kamalpour, S. Zekri, Raisa Aringazina, Ramazon Safarzoda, Amin Tamadon, Nader Tanideh

Bibliographic record

VenueJournal of Infertility and Reproductive Biology · 2025
Typereview
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicPharmacological Effects of Natural Compounds
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsPolycystic ovaryMedicinal plantsMedicineTraditional medicineOvaryInternal medicineInsulin resistanceObesity

Abstract

fetched live from OpenAlex

Polycystic ovary syndrome (PCOS) represents one of the most common endocrine disorders affecting women of reproductive age, serving as a major contributor to infertility on a global scale, with an estimated prevalence varying from 6 to 20% worldwide. PCOS is a complex syndrome defined by hyperandrogenism, irregular ovulation, and the presence of polycystic ovarian morphology. This syndrome is often associated with metabolic complications, including obesity, dyslipidemia, and an elevated risk of insulin resistance and developing type 2 diabetes. Symptoms include menstrual irregularities, weight gain, hirsutism, acne, and infertility. The presently available conventional treatment options for PCOS include hormonal contraceptives, insulin sensitizers, anti-androgens, and ovulation-inducing agents. While these treatments may offer symptomatic relief, they often entail potential side effects and do not adequately address the underlying cause of this syndrome. Herbal remedies have been used for centuries across cultures to manage various disorders due to their cost efficiency, availability, and safe nature. Several studies have demonstrated the efficiency of herbal remedies in the treatment of female reproductive disorders, including PCOS. This review comprises an extensive survey of the latest animal and clinical studies concerning plants and phytochemicals that have demonstrated effectiveness in alleviating symptoms associated with PCOS, as well as treating the underlying mechanisms involved in their efficacy

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.953
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0040.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.160
GPT teacher head0.495
Teacher spread0.336 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueJournal of Infertility and Reproductive BiologySame topicPharmacological Effects of Natural CompoundsFrench-language works237,207