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Record W4410829732 · doi:10.7759/cureus.84944

Trends in Prescription Medication Use for Depression Symptoms: An Analysis of National Health Interview Survey (NHIS) Data From 2019 to 2023

2025· article· en· W4410829732 on OpenAlexaff
Feyisayo O Oguntuase, Okelue E Okobi, Ogunsemi Olawale, Osatohanmwen Irorere, Oluwatayo A Dare, Nnenna B Emejuru, Roseline Igbadumhe, Oyindamola D Duyilemi, Saliu A Shittu, Erhieyovbe Emore

Bibliographic record

VenueCureus · 2025
Typearticle
Languageen
FieldPsychology
TopicMental Health Treatment and Access
Canadian institutionsFoothills Medical Centre
Fundersnot available
KeywordsMedicineNational Health Interview SurveyMedical prescriptionDepression (economics)PsychiatryFamily medicineEnvironmental healthPharmacologyPopulation

Abstract

fetched live from OpenAlex

Background: Depression is a major public health concern, and antidepressant medication is commonly prescribed for its management. Understanding trends in antidepressant use across socio-demographic groups is crucial for targeted interventions. Objective: To analyze trends in antidepressant medication use between 2019 and 2023 using data from the National Health Interview Survey (NHIS), focusing on demographic factors such as gender, age, race, and social vulnerability. Method: Data from the NHIS (2019-2023) were analyzed to assess trends in antidepressant use by sociodemographic variables. Descriptive statistics and trends were evaluated using prevalence estimates with confidence intervals. Result: Overall, antidepressant use increased from 9.8% (95% CI: 9.4-10.3) in 2019 to 11.4% (95% CI: 11.0-11.9) in 2023 (p-trend <0.001). The most notable increases were observed among females (13.3% in 2019 to 15.3% in 2023; p-trend <0.05), individuals aged 45-64 years (p-trend <0.05), and those with higher social vulnerability (p-trend =0.004). Racial disparities persisted, with White individuals showing the highest use of antidepressants (11.2% in 2019 to 13.2% in 2023; p-trend <0.05). Use was significantly higher among those with disabilities compared to those without (27.7% vs. 8.1% in 2019; 28.2% vs. 9.7% in 2023; p <0.001). Conclusion: The study reveals a steady increase in antidepressant use from 2019 to 2023, particularly among females, older adults, and individuals with higher social vulnerability or disabilities. Racial disparities in antidepressant use persist, with White individuals showing the highest prevalence. These findings highlight the ongoing need for targeted mental health interventions, especially for vulnerable groups, and underscore the importance of addressing disparities in access to mental health care. Future research should focus on the factors driving these trends and their implications for public health.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.102
Threshold uncertainty score0.203

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.003
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.244
GPT teacher head0.516
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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