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Record W4410868789 · doi:10.1016/j.cdnut.2025.106787

Bioavailability of Contaminants in Human Milk and Infant Formula When Consumed by the Infant: A Systematic Review

2025· review· en· W4410868789 on OpenAlexaff
Shailesh Advani, Lauren E O’Connor, Rachel C Thoerig, Cassi N Uffelman, Maureen K Spill, Arin A. Balalian, Trish Bosse, M. Foster, Kyle M Holland, Kathryn G. Dewey, Mandy Fisher, Aubrey L. Galusha, Carin Huset, Jessica L. Reiner, Amanda J MacFarlane

Bibliographic record

VenueCurrent Developments in Nutrition · 2025
Typereview
Languageen
FieldNursing
TopicInfant Nutrition and Health
Canadian institutionsHealth Canada
Fundersnot available
KeywordsInfant formulaBioavailabilityContaminationFood scienceEnvironmental scienceChemistryBiologyPharmacologyEcology

Abstract

fetched live from OpenAlex

postpartum period demands increased nutrition due to tissue repair, blood loss during delivery, breastfeeding, and hormonal changes.This study evaluated postpartum anemia prevalence among new mothers in Kumasi, Ghana, examining relationships between maternal diet quality, food security, and anemia risk.Methods: This cross-sectional study conducted in Kumasi, Ghana, involved 104 exclusively breastfeeding women with babies aged !1 week but 6months.Participants were recruited by a simple random sampling.Data on socio-demographics and obstetric history were collected using structured questionnaires, while dietary diversity and food security were assessed using standard questionnaires.Maternal hemoglobin(Hb) levels were measured using the Urit Hemoglobin Analysis Tester Meter.Descriptive analysis, Chi-Square Test of Goodness Fit and Chi-Square Test of Independence were conducted.Results: Descriptive analysis showed that 54.8% of mothers met the minimum dietary diversity for women (MDD-W).While 56.7% had high food security, 37.5% were food insecure -with higher rates in suburban areas and among those with monthly incomes (below 500 cedis /$35).Food insecurity was nearly twice as common in mothers who did not meet MDD-W compared to those who did.Regarding anemia, 51.9% of mothers showed varying levels of anemia, while 48.1% had normal Hb concentrations.Low rates of anemia were recorded among mothers living in urban areas than their counterparts in sub-urban areas.The rate of anemia was lower among mothers who had their child by vaginal birth than by cesarean section.Despite high rates of anemia, mothers who were food insecure, or anemic were less than expected (p < 0.001).Anemia among mothers with high food security was less than expected, while more food insecure mothers had anemia.Although the study did not have enough evidence to prove any association between anemia, food security and the MDD-W, the study highlights the need for further studies to investigate these associations.Conclusions: The results of this study indicate a high rate of PPA among mothers in Kumasi.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.239
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.381
Teacher spread0.335 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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