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Record W4410876562 · doi:10.1016/j.bbr.2025.115675

Promoting brain health and resilience: The effect of three types of acute exercise on affect, brain-derived neurotrophic factor and heart rate variability

2025· article· en· W4410876562 on OpenAlexafffund
Thomas Rawliuk, Mikal Thrones, Dean M. Cordingley, Stephen M. Cornish, Steven G. Greening

Bibliographic record

VenueBehavioural Brain Research · 2025
Typearticle
Languageen
FieldMedicine
TopicHeart Rate Variability and Autonomic Control
Canadian institutionsPan Am ClinicUniversity of Manitoba
FundersUniversity of Manitoba
KeywordsAffect (linguistics)Brain-derived neurotrophic factorNeurotrophic factorsNeurosciencePsychologyHeart rate variabilityHeart rateMedicineInternal medicineReceptor

Abstract

fetched live from OpenAlex

Physical exercise supports brain health and resilience through a variety of factors involving affective states, neurotrophins, and autonomic activity. These factors play a crucial role in supporting mental and physical health across the lifespan. We evaluated the acute effects of moderate-intensity continuous exercise, high-intensity interval exercise, and resistance exercise on positive and negative affect, Brain Derived Neurotrophic Factor (BDNF), and Heart Rate Variability (HRV). In a repeated measures cross-over design, 12 participants over 5 weeks underwent all three exercise types while affect, phlebotomy, and cardiac, measures were taken pre-, immediately post-, 30-minutes, and 60-minutes post-exercise. We found an increase in plasma BDNF concentrations irrespective of exercise type from immediately pre-exercise to post-exercise. The HRV analysis identified a decrease in root mean square of successive differences (RMSSD) immediately post-exercise, followed by a gradual increase to above pre-exercise levels at 60-minutes post exercise. We also observed a decrease in negative affect following exercise that was sustained till 60-minutes post-exercise. Taken together, the results suggest that although exercise type did not differentially affect negative affect, BDNF, or HRV, all three measures suggested a consistent physiological and psychological improvement post-exercise, highlighting the potential benefits of various forms of exercise on aspects of brain health and resilience.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.009
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.691
Threshold uncertainty score0.617

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0090.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.382
Teacher spread0.336 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes2
Has abstractyes

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