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Record W4410932173 · doi:10.1186/s42490-025-00092-6

High-frequency signals: a comparison between the cable equation and telegrapher’s equations in nerves

2025· article· en· W4410932173 on OpenAlexaff
Paul Potgieter, Petra van Blerk, Corlius Fourie Birkill

Bibliographic record

VenueBMC Biomedical Engineering · 2025
Typearticle
Languageen
FieldNeuroscience
TopicNeuroscience and Neural Engineering
Canadian institutionsBritish Columbia Institute of Technology
Fundersnot available
KeywordsTelegrapher's equationsFrequency domainInductanceSalientCable theoryMathematical analysisAcousticsPhysicsMathematicsComputer scienceTransmission lineTelecommunicationsVoltageCable harness

Abstract

fetched live from OpenAlex

Transmission of electrical impulses along axons is commonly modelled with the cable equation, which neglects the inductive effects that have been measured in nerves. By using the telegrapher's equations, it is possible to incorporate inductive effects and compare with the non-inductive case. Although both of these approaches have been extensively studied, the question remains as to which of these provides a more accurate model of human physiology. Many of the electrical properties of nerves are frequency-dependent, a fact which is not very relevant in a low-frequency domain, but which becomes salient when higher frequencies are considered, and necessitates the exploration of the magnitude of their effects. We compare the effects of both inductance and other variable parameters across a wide frequency range using both the cable equation and the telegrapher's equations, demonstrating that it is possible for axons to transmit high-frequency signals much more effectively than might be expected, especially in the absence of an action potential. This implies that the high-frequency domain necessitates use of the more complete model.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.003
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.054
GPT teacher head0.292
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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