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Record W4410945763 · doi:10.1101/2025.05.30.25328681

Poor Sleep Health Early After Stroke is Associated with Lower Quality of Life Later After Stroke

2025· preprint· en· W4410945763 on OpenAlexaboutno aff
George Fulk, Karen J. Klingman, Emily Peterson

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldMedicine
TopicStroke Rehabilitation and Recovery
Canadian institutionsnot available
FundersNational Institute of Nursing ResearchNational Institutes of Health
KeywordsStroke (engine)Montreal Cognitive AssessmentMedicinePsychological interventionPhysical therapyQuality of life (healthcare)AlertnessRehabilitationActigraphyPhysical medicine and rehabilitationCognitionInternal medicineCognitive impairmentPsychiatryCircadian rhythm

Abstract

fetched live from OpenAlex

Background: Factors early after stroke that are predictive of outcomes can help guide rehabilitation interventions. There is a growing understanding of the importance of sleep for recovery after stroke. Objectives: To explore factors at 10 days post stroke, including sleep health (SH), that may be associated with QOL at 60 days post stroke. Methods: Data from 62 participants were collected at 10 and 60 days post stroke. Independent variables at 10 days post stroke were the NIHSS, Barthel Index (BI), Montreal Cognitive Assessment (MOCA), Patient Health Questionnaire (PHQ-9), gait speed, Berg Balance Scale, and SH. SH was measured by combining data from actigraphy and self-report to create a score that reflected regularity, satisfaction, alertness, timing, efficiency, and duration of sleep (S-Ru-SATED). The Stroke Impact Scale (SIS) at 60 days post stroke assessed quality of life. A multiple linear regression using a leave-one-out cross validation was employed to assess the association between the independent variables at 10 days and the SIS at 60 days. Results: The leave-one-out cross-validation analysis revealed that MOCA (p=0.0068), NIHSS (p=0.0181), BI (p=0.0028), and S-Ru-SATED (p=0.000155) at 10 days post stroke were significantly associated with the SIS at 60 days post stroke. Conclusions: Participants with less stroke severity, higher cognition, better functional ability, and better SH early after stroke were more likely to have a higher QOL at 2 months post stroke. Research is needed to assess the impact of interventions to improve SH in conjunction with rehabilitation interventions after stroke.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.303
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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