Gluten-Induced Hemoptysis: A Case Report of Lane–Hamilton Syndrome
Bibliographic record
Abstract
Lane–Hamilton syndrome describes the co-occurrence of idiopathic pulmonary hemosiderosis and celiac disease. A 24-year-old man presented with fatigue and several weeks of scant hemoptysis. Investigations revealed profound anemia and left lower lobe ground-glass opacities on computed tomography scan of the chest. Transbronchial biopsies showed hemosiderin-laden macrophages. Ancillary investigations revealed elevated tissue transglutaminase level and celiac disease was confirmed on duodenal biopsy despite the absence of gastrointestinal symptoms. He was treated with a gluten-free diet and a tapering course of prednisone with excellent response. This case highlights that hemoptysis can be the only presenting symptom for Lane–Hamilton syndrome, warranting thorough investigations for celiac disease.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.009 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".