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Record W4411015442 · doi:10.1115/dmd2025-1098

Compression-Aided Millisecond-Scale Cauterization and its Application in Achieving Concurrent Hemostasis During Powered Tissue Resection

2025· article· en· W4411015442 on OpenAlexaff
Matteo Bomben, Thomas Looi, Naomi Matsuura, James M. Drake

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicHemostasis and retained surgical items
Canadian institutionsHospital for Sick ChildrenUniversity of Toronto
Fundersnot available
KeywordsCauterizationMillisecondHemostasisComputer scienceCompression (physics)Scale (ratio)ResectionMaterials scienceSurgeryMedicinePhysics

Abstract

fetched live from OpenAlex

Abstract Motorized tissue shavers are commonly used to rapidly fragment and remove intraventricular brain tumors during endoscopic neurosurgery. However, a key drawback of these devices is that they cannot be used on vascularized tumors as unmanageable levels of bleeding are encountered when they are fragmented. This problem could be addressed by concurrently applying a radiofrequency (RF) current to cauterize the tumor tissue as it is shaved, but this approach would require that cauterization occur in less than 50 ms. In this work, we investigated whether simultaneous tissue compression paired with a RF current can be used to achieve cauterization in millisecond timescales and then integrated this technique into the design of a combined cautery-shaver mechanism. We began by using both finite element modelling and benchtop experiments to demonstrate that cauterization occurs in timeframes as short as 15 ms if tissue is simultaneously compressed during RF current application. Based on these results, a novel shaver device that compresses and cauterizes tissue just prior to fragmentation was developed. Proof-of-concept prototypes demonstrated the design’s ability to both resect and rapidly cauterize tissue. Finally, we fabricated a fully mechanized version of the device that could execute a single tissue resection cycle on command. Testing on ex vivo brain samples showed that the tool successfully cauterized tissue to the depth necessary for hemostasis while simultaneously resecting a mass of tissue comparable to that removed by existing shaver tools.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.268
Threshold uncertainty score0.411

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.306
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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