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Record W4411048991 · doi:10.1016/j.jad.2025.119615

Early experiences of maternal warmth buffer against effects of proximal stress on neural responses to reward in a sample of adult women

2025· article· en· W4411048991 on OpenAlexafffund
Corinne Sejourne, Clara Freeman, Aislinn Sandre, Melanie A. Dirks, Iulia Banica Malcolm, Paige Ethridge, Anna Weinberg

Bibliographic record

VenueJournal of Affective Disorders · 2025
Typearticle
Languageen
FieldPsychology
TopicChild and Adolescent Psychosocial and Emotional Development
Canadian institutionsGlenrose Rehabilitation HospitalOntario Shores Centre for Mental Health SciencesMcGill University
FundersCanadian Institutes of Health ResearchCanada Excellence Research Chairs, Government of Canada
KeywordsPsychologyDevelopmental psychologyPsychopathologyStress (linguistics)Neural correlates of consciousnessMaternal deprivationClinical psychologyEvent-related potentialYoung adultInterpersonal communicationMaternal sensitivityAudiologyMedicineCognitionPsychiatrySocial psychology

Abstract

fetched live from OpenAlex

The link between stress exposure and psychopathology is well-established, and may be due in part to the blunting effects of stress exposure on neural responses to rewards. Identification of factors that buffer against the adverse effects of stress exposure is therefore important. Early caregiving experiences of warmth and sensitivity have been shown to influence stress susceptibility later in life. The present study sought to investigate whether early maternal care moderates the effect of proximal interpersonal stress exposure on the neural processing of rewards in adult women. Two reward-sensitive event-related potential (ERP) components were examined: the P200 (P2) and the Reward Positivity (RewP). Eighty-nine women completed 1) the self-report Parental Bonding Instrument (PBI) to assess early experiences of parenting, 2) a semi-structured interview to assess recent stress exposure, and 3) a peer interaction 'Survivor'-style task to elicit neural responses to social acceptance. Analyses revealed a significant interaction between maternal care and current stress on P2 amplitude (β = 0.21, p = .04), and a similar, though not statistically significant, effect on the RewP in terms of magnitude and direction (β = 0.18, p = .09). These results suggest that, in women reporting low levels of early maternal warmth, higher levels of recent stress exposure were associated with blunted neural response to rewards. Proximal stress was not associated with these neural responses in women reporting medium or high levels of early maternal warmth. These findings suggest that warm, sensitive parenting in early life may influence stress sensitivity into adulthood.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.278
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes2
Has abstractno

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