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Record W4411075077 · doi:10.1038/s41591-025-03759-8

The People-First Liver Charter

2025· article· en· W4411075077 on OpenAlexafffund
Jeffrey V. Lazarus, Dana Ivancovsky‐Wajcman, Silvana Pannain, Paul Brennan, Melina I. Manolas, Peter Jepsen, Carla Treloar, Anish Arora, Philippa C. Matthews, Camila A Picchio, Trenton M. White, Jason Grebely, Juan Vaz, Hannes Hagström, Kenneth Rabin, Scott Isaacs, Michael Roden, Michael Betel, José Willemse, Luis Antonio Díaz, Alina M. Allen, Naim Alkhouri, Jörn M. Schattenberg, Dı́dac Mauricio, Mary E. Rinella, Elisa Pose, Emmanuel Tsochatzis, Michael Ninburg, Kenneth Cusi, William Alazawi, Ajay Duseja, Gema Frühbeck, Priya Jaisinghani, Fasiha Kanwal, Gamal Shiha, Shira Zelber‐Sagi, Marcela Villota‐Rivas

Bibliographic record

VenueNature Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicLiver Disease Diagnosis and Treatment
Canadian institutionsMcMaster University
FundersNational Institute of Allergy and Infectious DiseasesFaculty of Medicine and Health, University of SydneyAgencia Estatal de InvestigaciónSahlgrenska AkademinSchool of Medicine, Emory UniversityIpsenEuropean Association for the Study of the LiverNovo NordiskKarolinska InstitutetEisaiGeneralitat de CatalunyaUniversity College LondonNGM BiopharmaceuticalsIntercept PharmaceuticalsInventiva PharmaKowa CompanyIonis PharmaceuticalsBristol-Myers SquibbCentres de Recerca de CatalunyaFrancis Crick InstituteCity University of New YorkNational Institutes of HealthRegeneron PharmaceuticalsGöteborgs UniversitetCentro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y NutriciónNovavaxUniversity of FloridaAmerican Diabetes AssociationEmory UniversityNational Institute for Health and Care ResearchQueen Mary University of LondonAarhus UniversitetshospitalGilead SciencesUniversity of New South WalesAlexion PharmaceuticalsMcMaster UniversityModernaPfizerAmerican Association for the Study of Liver DiseasesGenentechAstraZenecaEli Lilly and CompanyInstituto de Salud Carlos IIISiemens HealthineersUniversitat de BarcelonaAmgenAarhus UniversitetSanofiGW PharmaceuticalsUniversity of Dundee
KeywordsCharterMedicinePolitical scienceLaw

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.726
Threshold uncertainty score0.367

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.275
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations15
Published2025
Admission routes2
Has abstractno

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