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Record W4411077275 · doi:10.1016/j.ajcnut.2025.06.003

Paving the way for improved action: how nuclear techniques can advance the assessment of malnutrition

2025· article· en· W4411077275 on OpenAlexaff
Shruti P. Shertukde, Ramya Padmanabha, Stephanie T. Chung, Claire Gaudichon, Kerry S. Jones, Paul Kelly, Nancy F. Krebs, Anura V. Kurpad, Yvonne Lamers, Veronica Lopez‐Teros, Alida Melse‐Boonstra, Fátima C. Pereira, Carla M. Prado, Susan B. Roberts, John R. Shepherd, Pattanee Winichagoon, Jonathan C. K. Wells, Cornelia Loechl, Daniël J. Hoffman

Bibliographic record

VenueAmerican Journal of Clinical Nutrition · 2025
Typearticle
Languageen
FieldMedicine
TopicNutrition and Health in Aging
Canadian institutionsUniversity of AlbertaUniversity of British Columbia
FundersNational Institutes of HealthInternational Atomic Energy Agency
KeywordsAction (physics)MalnutritionRisk analysis (engineering)Computer scienceMedicineInternal medicinePhysics

Abstract

fetched live from OpenAlex

Malnutrition in all its forms-including undernutrition, micronutrient deficiencies, and overnutrition-continues to rise globally, driven by complex structural and biological factors that contribute to an increased risk of noncommunicable diseases (NCDs). Addressing this multifaceted challenge requires precise assessment tools. To advance this effort, the International Atomic Energy Agency held a technical meeting of global experts to explore how nuclear techniques, specifically stable isotope tracers and imaging methods, and emerging technologies can enhance nutrition assessments to better address malnutrition. On the basis of the meeting's discussions, this report highlights the application of nuclear techniques to improve the measurement of body composition across life stages and disease states, assess nutrient bioavailability more holistically, elucidate nutrient flux under conditions of malnutrition, trace metabolic processes linked to NCDs, and refine nutrient requirements to better reflect diverse populations. The integration of nuclear techniques with emerging tools such as artificial intelligence and model-based compartmental analysis was emphasized as a key strategy to enhance their utility. This report also highlights the important role of nuclear techniques in addressing malnutrition and calls for interdisciplinary collaboration and reduced research silos to fully leverage these techniques to combat this condition more effectively.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.016
metaresearch head score (Gemma)0.038
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.016
Threshold uncertainty score0.083

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0160.038
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0030.001
Science and technology studies0.0020.007
Scholarly communication0.0090.011
Open science0.0020.004
Research integrity0.0070.010
Insufficient payload (model declined to judge)0.0100.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.067
GPT teacher head0.492
Teacher spread0.425 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractno

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