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Record W4411089766 · doi:10.1016/j.nutos.2025.06.001

Dietary biomarkers of ultra-processed foods: A narrative review

2025· review· en· W4411089766 on OpenAlexfundno aff
Thomas Scott Armstrong, Kaitlyn Delaney Chappell, Lekan Ajibulu, Karen Wong

Bibliographic record

VenueClinical Nutrition Open Science · 2025
Typereview
Languageen
FieldMedicine
TopicConsumer Attitudes and Food Labeling
Canadian institutionsnot available
FundersUniversity of Alberta
KeywordsFood scienceNarrative reviewMedicineChemistryIntensive care medicine

Abstract

fetched live from OpenAlex

<h2>Summary</h2> The rapidly increasing prevalence of ultra-processed foods (UPFs) in global diets necessitates a more comprehensive understanding of this food group's effects on health and disease. Nutritional biomarkers are critical for developing this understanding, as they provide an objective assessment of the body's response to UPF intake. Here, we critically assessed the findings of five studies-all of which were identified via a systematic search of the literature using stringent criteria and were focused on the biomarkers of UPFs. Based on the data extracted, we categorized UPF biomarkers into organic acids (including amino acids), lipids/lipid-like molecules, xenobiotic food components (specifically associated with UPFs), and other molecular compounds (dietary oxysterols, nucleotides, proteins, etc). These findings emphasized the importance of future studies concerning UPF and food processing techniques, while providing a succinct summary of the current biomarkers of UPFs in relevant literature.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.750
Threshold uncertainty score0.963

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0000.003
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0020.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.208
GPT teacher head0.531
Teacher spread0.323 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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