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Record W4411109517 · doi:10.1002/nano.70021

Copolymerization of Hydrophilic and Hydrophobic Monomers in Water Assisted by Cyclodextrins

2025· article· en· W4411109517 on OpenAlex
Alexy Sanseigne, Guillaume Beaudoin, Ka Ho Yau, X. X. Zhu

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueNano Select · 2025
Typearticle
Languageen
FieldChemistry
TopicAdvanced Polymer Synthesis and Characterization
Canadian institutionsUniversité de Montréal
FundersFonds Québécois de la Recherche sur la Nature et les TechnologiesNatural Sciences and Engineering Research Council of CanadaCanada Research Chairs
KeywordsCopolymerMonomerCyclodextrinPolymer chemistryHydrophobic effectChemical engineeringChemistryHydrophobeMaterials scienceOrganic chemistryPolymerBiochemistry

Abstract

fetched live from OpenAlex

ABSTRACT To facilitate the copolymerization of both hydrophobic and hydrophilic monomers in aqueous media, cyclodextrins (CDs) are introduced to form inclusion complexes with the hydrophobic monomers. As a proof of concept, β‐CD is used to solubilize a hydrophobic acrylamide derivative of cholic acid (CAAM) in water, enabling its copolymerization with acrylamide to occur in a common and benign solvent, that is, water. An excess of β‐CD is needed to effectively solubilize the cholic acid monomer CAAM in water, leading to the synthesis of a thermoresponsive polymer. The CAAM content in the final copolymer is ca. 2.5 mol%, in contrast to the 5 mol% contained in the feed. Notably, this investigation underscores the usefulness of inclusion complexation in the copolymerization process. The same monomer formed a looser inclusion complex with γ‐CD, which has a larger cavity than β‐CD, and produced a copolymer with only 0.74 mol% of CAAM, indicating the importance of the stability of complexation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.016
Threshold uncertainty score0.448

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.206
Teacher spread0.204 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it