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Record W4411116050 · doi:10.1186/s12940-025-01153-y

Extreme heat and pediatric health in a warming world: a space-time stratified case-crossover investigation in Ontario, Canada

2025· article· en· W4411116050 on OpenAlexafffundabout
Hallah Kassem, Éric Lavigne, Kate R. Weinberger, Michael Bräuer

Bibliographic record

VenueEnvironmental Health · 2025
Typearticle
Languageen
FieldEnvironmental Science
TopicClimate Change and Health Impacts
Canadian institutionsOttawa Public HealthHealth CanadaUniversity of British Columbia
FundersHealth CanadaBanting Research FoundationNational Aeronautics and Space Administration
KeywordsMedicinePercentileAsthmaPoisson regressionPsychological interventionPediatricsDemographyEmergency medicineEnvironmental healthPopulationInternal medicineNursing

Abstract

fetched live from OpenAlex

BACKGROUND: Globally, climate change is causing frequent and severe extreme heat events (EHEs). A large body of literature links EHEs to multiple health endpoints. While children's physiology and activity patterns differ from those of adults in ways that are hypothesized to increase susceptibility to such endpoints, research gaps remain regarding the specific impacts of EHEs on child health. This study evaluated pediatric emergency healthcare utilizations associated with EHEs in Ontario. METHODS: Applying a space-time stratified case-crossover design, associations between EHEs (same-day or lagged exposure to 2 consecutive days of daily maximum temperatures above percentile thresholds) and 15 causes of pediatric emergency healthcare use in Ontario, Canada from 2005 to 2015 were analysed using conditional quasi-Poisson regression. In primary analyses, EHEs were defined as two or more consecutive days with temperatures above the 99th percentile of temperature within each respective forward sortation area (FSA). Emergency healthcare use was measured using hospital admissions as an indicator of severe outcomes, and emergency department (ED) visits as a sensitive measure of outcomes. RESULTS: Relative to non-EHE days, EHEs increased the rates of pediatric hospital admissions for respiratory illnesses by 26% (95% CI: 14-40%), asthma by 29% (16-44%); infectious and parasitic diseases by 36% (24-50%), lower respiratory infections by 50% (36-67%), and enteritis by 19% (7-32%). EHEs also increased the rates of ED visits for lower respiratory infections by 10% (0-21%), asthma by 18% (7-29%), heat-related illnesses by 211% (193-230%), heatstroke by 590% (550-622%), and dehydration by 35% (25-46%), but not for other causes. Admissions and ED visits due to injuries and transportation related injuries were negatively associated with EHEs. Neither all-cause hospital admissions nor ED visits were associated with EHEs. CONCLUSIONS: In Ontario, EHEs decreased the rates of pediatric emergency healthcare utilization for injuries and increased the rates of respiratory illnesses, asthma, heat-related illnesses, heatstroke, dehydration, infectious and parasitic diseases, lower respiratory infections, and enteritis. Tailored policies and programs that reflect the specific heat-related vulnerabilities of children to respiratory and infectious illnesses are warranted in the face of a rapidly warming climate.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.266
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2025
Admission routes3
Has abstractyes

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