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Record W4411135953 · doi:10.1186/s12875-025-02785-2

Opportunities, challenges, and requirements for Artificial Intelligence (AI) implementation in Primary Health Care (PHC): a systematic review

2025· review· en· W4411135953 on OpenAlex
Farzaneh Yousefi, Reza Dehnavieh, Maude Laberge, Marie-Pierre Gagnon, Mohammad Mehdi Ghaemi, Mohsen Nadali, Najmeh Azizi

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueBMC Primary Care · 2025
Typereview
Languageen
FieldMedicine
TopicArtificial Intelligence in Healthcare and Education
Canadian institutionsUniversité Laval
Fundersnot available
KeywordsPrimary carePrimary health careMedicineComputer scienceHealth carePolitical scienceFamily medicine

Abstract

fetched live from OpenAlex

BACKGROUND: Artificial Intelligence (AI) has significantly reshaped Primary Health Care (PHC), offering various possibilities and complexities across all functional dimensions. The objective is to review and synthesize available evidence on the opportunities, challenges, and requirements of AI implementation in PHC based on the Primary Care Evaluation Tool (PCET). METHODS: We conducted a systematic review, following the Cochrane Collaboration method, to identify the latest evidence regarding AI implementation in PHC. A comprehensive search across eight databases- PubMed, Web of Science, Scopus, Science Direct, Embase, CINAHL, IEEE, and Cochrane was conducted using MeSH terms alongside the SPIDER framework to pinpoint quantitative and qualitative literature published from 2000 to 2024. Two reviewers independently applied inclusion and exclusion criteria, guided by the SPIDER framework, to review full texts and extract data. We synthesized extracted data from the study characteristics, opportunities, challenges, and requirements, employing thematic-framework analysis, according to the PCET model. The quality of the studies was evaluated using the JBI critical appraisal tools. RESULTS: In this review, we included a total of 109 articles, most of which were conducted in North America (n = 49, 44%), followed by Europe (n = 36, 33%). The included studies employed a diverse range of study designs. Using the PCET model, we categorized AI-related opportunities, challenges, and requirements across four key dimensions. The greatest opportunities for AI integration in PHC were centered on enhancing comprehensive service delivery, particularly by improving diagnostic accuracy, optimizing screening programs, and advancing early disease prediction. However, the most challenges emerged within the stewardship and resource generation functions, with key concerns related to data security and privacy, technical performance issues, and limitations in data accessibility. Ensuring successful AI integration requires a robust stewardship function, strategic investments in resource generation, and a collaborative approach that fosters co-development, scientific advancements, and continuous evaluation. CONCLUSIONS: Successful AI integration in PHC requires a coordinated, multidimensional approach, with stewardship, resource generation, and financing playing key roles in enabling service delivery. Addressing existing knowledge gaps, examining interactions among these dimensions, and fostering a collaborative approach in developing AI solutions among stakeholders are essential steps toward achieving an equitable and efficient AI-driven PHC system. PROTOCOL: Registered in Open Science Framework (OSF) ( https://doi.org/10.17605/OSF.IO/HG2DV ).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.488
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.444
GPT teacher head0.519
Teacher spread0.075 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it