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Record W4411158301 · doi:10.3390/ani15121700

The Impact of a Multi-Strain Probiotic Supplementation on Puppies Manifesting Diarrhoeic Symptoms During the Initial Seven Days of Life

2025· article· en· W4411158301 on OpenAlexaboutno aff
Piotr Socha, Barbara Socha

Bibliographic record

VenueAnimals · 2025
Typearticle
Languageen
FieldHealth Professions
TopicInfant Health and Development
Canadian institutionsnot available
Fundersnot available
KeywordsProbioticStrain (injury)MedicinePediatricsBiologyInternal medicineGenetics

Abstract

fetched live from OpenAlex

Acute diarrhoea is a prevalent condition in puppies, frequently accompanied by a reduction in daily weight gain and an elevated risk of mortality. The utilisation of probiotics has been demonstrated to facilitate the restoration of intestinal microflora homeostasis. To date, limited research has investigated the effect of probiotics on reducing diarrhoea in very young puppies fed exclusively on mother’s milk. The aim of the present study was to evaluate the impact of administering a multi-strain probiotic on reducing diarrhoeic symptoms in puppies during their first seven days of life. A total of 77 Labrador Retriever puppies, aged between one and seven days, were examined. The study found that 55% of the puppies presented with clinical symptoms of diarrhoea. The puppies exhibiting diarrhoea were administered a multi-strain probiotic comprising the Lactobacillus plantarum AMT4 and AMT14 strains and the Bifidobacterium animalis AMT30 strain for a period of five days in monotherapy. The results demonstrated that within 24 h of the first dose, a reduction in the incidence of diarrhoeic symptoms was observed in 47.62% of the dogs. Following a 72 h period, 83.34% of the puppies exhibited a resolution of their symptoms. The animals that were part of the study demonstrated expected weight gain and were in good condition. The preliminary study confirmed the high effectiveness of the multi-strain probiotic in halting diarrhoea in puppies up to seven days of age. The results obtained from this study are highly promising and provide new perspectives on the treatment of diarrhoea in puppies fed exclusively on their mother’s milk.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.112
Threshold uncertainty score0.748

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.451
Teacher spread0.392 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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