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Record W4411180354 · doi:10.1148/radiol.243450

Diagnostic Performance of CT/MRI LI-RADS Version 2018 Major Feature Combinations: Individual Participant Data Meta-Analysis

2025· review· en· W4411180354 on OpenAlexafffund
Robert G. Adamo, Christian B. van der Pol, Mostafa Alabousi, Eric Lam, Jean‐Paul Salameh, Nicole Abedrabbo, Emily Lerner, Haresh Naringrekar, Andreu F. Costa, Hoda Osman, Brooke Levis, Adam Polikoff, Alessandro Furlan, An Tang, Andrea S. Kierans, Amit G. Singal, Ashwini Arvind, Ayman S. Alhasan, Brian C. Allen, Caecilia S. Reiner, Christopher Clarke, Daniel R. Ludwig, Federico Díaz Telli, Federico Piñero, Grzegorz Rosiak, Hanyu Jiang, Heejin Kwon, Hong Wei, Hyo‐Jin Kang, Ijin Joo, Jeong Ah Hwang, Ji Hye Min, Ji Soo Song, Jin Wang, Joanna Podgórska, John R. Eisenbrey, Krzysztof Bartnik, Li‐Da Chen, Marco Dioguardi Burgio, Maxime Ronot, Milena Cerny, Nieun Seo, Shengxiang Rao, Roberto Cannella, Sang Hyun Choi, Tyler J. Fraum, Wentao Wang, Woo Kyoung Jeong, Xiang Jing, Yeun‐Yoon Kim, Matthew D. F. McInnes

Bibliographic record

VenueRadiology · 2025
Typereview
Languageen
FieldMedicine
TopicRadiomics and Machine Learning in Medical Imaging
Canadian institutionsCentre Hospitalier de l’Université de MontréalMcGill UniversityQueen Elizabeth II Health Sciences CentreOttawa HospitalJuravinski HospitalDalhousie UniversityHamilton Health SciencesUniversity of Ottawa
FundersCanadian Institutes of Health ResearchNational Natural Science Foundation of ChinaFonds de Recherche du Québec - SantéMach-Gaensslen Foundation of CanadaRSNA Research and Education Foundation
KeywordsMedicineFeature (linguistics)BI-RADSRadiologyNuclear medicineMeta-analysisMedical physicsPathologyInternal medicine

Abstract

fetched live from OpenAlex

This meta-analysis showed that most major feature combinations in the same CT/MRI Liver Imaging Reporting and Data System category had similar positive predictive values for hepatocellular carcinoma in patients at high risk for cancer, with the exception of five combinations from LR-3 to LR-5.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.345
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0050.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.128
GPT teacher head0.401
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2025
Admission routes2
Has abstractyes

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