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Record W4411201828 · doi:10.1016/j.ssmmh.2025.100475

The association between mental health self-stigma and multiple mental health conditions: A systematic review

2025· review· en· W4411201828 on OpenAlexafffund
Lisa D. Hawke, Abigail Amartey, Péter Szatmári, Nicole Kozloff, Muhammad Ishrat Husain, Louise Gallagher, Terri Rodak, Philip T. Yanos

Bibliographic record

VenueSSM - Mental Health · 2025
Typereview
Languageen
FieldPsychology
TopicMental Health Treatment and Access
Canadian institutionsHospital for Sick ChildrenUniversity of TorontoCentre for Addiction and Mental Health
FundersCanadian Institutes of Health ResearchUniversity of Toronto
KeywordsMental healthStigma (botany)Substance useAssociation (psychology)PsychologyPsychiatryClinical psychologyPsychotherapist

Abstract

fetched live from OpenAlex

Background Self-stigma is commonly experienced among people with mental health conditions, across disorders and across the lifespan, with negative impacts. Objective This systematic review aimed to synthesize the literature on self-stigma among people with multiple co-occurring mental health conditions, inclusive of substance use conditions. We further explored whether multiple mental health conditions are associated with an added burden of self-stigma compared to single conditions. Method A systematic search was conducted of Medline, APA PsycInfo, Embase, Cumulative Index to Nursing & Allied Health Literature (CINAHL), Web of Science, and Applied Social Sciences Index and Abstracts (ASSIA). A total of 9246 records were found. We included reports providing quantitative self-stigma scores of individuals with co-occurring mental health or co-occurring mental health and substance use conditions. Quality assessment was conducted. Data were summarized narratively and presented in table format. Results Eleven studies were included with results reported across a sample of 1774 cases. Findings support that substance use conditions may confer an additional burden of self-stigma, but not cannabis use disorder. Self-stigma seems to be high for select comorbidities, in the case of depression, anxiety, and personality disorders, although results are mixed and inconclusive. Negative presentations are associated with higher self-stigma, such as higher symptom levels and illness severity, and lower functioning. Conclusion Substantial self-stigma is associated with comorbid mental health and substance use conditions. However, the literature is not yet fully developed to understand whether and to what degree there might be an additive effect of multiple mental health conditions on self-stigma.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.308
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0060.001
Bibliometrics0.0000.001
Science and technology studies0.0050.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.468
Teacher spread0.412 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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