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Detecção de Micronúcleos em Linfócitos: Um Novo Dataset e Estudo de Caso com YOLOv11

2025· article· pt· W4411212069 on OpenAlexaff
Camile A. Barbosa, Gael F. Lima, Suy F. Hwang, Fabiana Farias de Lima, Filipe R. Cordeiro

Bibliographic record

Venuenot available
Typearticle
Languagept
FieldComputer Science
TopicDigital Imaging for Blood Diseases
Canadian institutionsNexen (Canada)
Fundersnot available
KeywordsPhysics

Abstract

fetched live from OpenAlex

A detecção de micronúcleos (MN) em linfócitos é essencial na biomedicina para avaliar danos genéticos e instabilidade cromossômica, sendo importante para estudos toxicológicos e diagnóstico de câncer. No entanto, a identificação manual é demorada e sujeita a erros. Neste trabalho, propomos uma abordagem automatizada utilizando a rede neural YOLOv11 para detecção de micronúcleos em células binucleadas. Para isso, construímos uma base de imagens coletadas do Centro Regional de Ciências Nucleares do Nordeste (CRCN), composta por 889 imagens, com anotações de localização de células binucleadas e micronúcleos. Resultados da análise de detecção mostram que o modelo utilizado alcançou precisão de 90,8% e revocação de 92,8%, demonstrando confiabilidade para aplicações clínicas. Além disso, o conjunto de dados desenvolvido contribui para futuras pesquisas na área, fornecendo uma base padronizada para avaliação de modelos de visão computacional aplicados à citogenética. A base de dados desenvolvida está disponível em https://doi.org/10.5281/zenodo.14947933.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.029
Threshold uncertainty score0.057

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0020.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.289
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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