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Record W4411215149 · doi:10.3390/biomedicines13061434

3D Printing in Nasal Reconstruction: Application-Based Evidence on What Works, When, and Why

2025· review· en· W4411215149 on OpenAlexaff
Raisa Chowdhury, Nisreen Al-Musaileem, Karanvir S. Raman, Dana Al-majid, Philip Solomon, Richard Rival

Bibliographic record

VenueBiomedicines · 2025
Typereview
Languageen
FieldMedicine
TopicNasal Surgery and Airway Studies
Canadian institutionsUniversity of TorontoMcGill UniversityMcGill University Health Centre
Fundersnot available
Keywords3D printingBiocompatible material3d printedStereolithographyComputer scienceRapid prototypingMedical physicsMedicineBiomedical engineeringEngineeringMechanical engineering

Abstract

fetched live from OpenAlex

Background: Nasal reconstruction requires a balance between aesthetic and functional restoration. Recent advances in three-dimensional (3D) printing have introduced new approaches to this field, enabling precise, patient-specific interventions. This review explores the applications, benefits, and challenges of integrating 3D printing in nasal reconstruction. Methods: A literature search was conducted using PubMed, Scopus, and Web of Science to identify studies on 3D printing in nasal reconstruction. Peer-reviewed articles and clinical trials were analyzed to assess the impact of 3D-printed models, implants, and bioengineered scaffolds. Results: 3D printing facilitates the creation of anatomical models, surgical guides, and implants, enhancing surgical precision and patient outcomes. Techniques such as stereolithography (SLA) and selective laser sintering (SLS) enable high-resolution, biocompatible constructs using materials like polylactic acid, titanium, and hydroxyapatite. Computational fluid dynamics (CFD) tools improve surgical planning by optimizing nasal airflow. Studies show that 3D-printed guides reduce operative time and improve symmetry. Emerging bioprinting techniques integrating autologous cells offer promise for tissue regeneration. Challenges and Future Directions: Challenges include high costs, imaging limitations, regulatory hurdles, and limited vascularization in bioprinted constructs. Future research should focus on integrating bioactive materials, artificial intelligence-assisted design, and regulatory standardization. Conclusions: 3D printing offers specific advantages in nasal reconstruction, improving precision and outcomes in selected cases. Addressing current limitations through technological and regulatory advancements will further its clinical integration, potentially enhancing reconstructive surgery techniques.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.976
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.357
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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