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Record W4411220929 · doi:10.1038/s44407-025-00014-9

The synergistic effects of PM2.5 and high temperature on community mortality in British Columbia

2025· article· en· W4411220929 on OpenAlexaffabout
Eric S. Coker, Stephanie E. Cleland, David A. McVea, Massimo Stafoggia, Sarah B. Henderson

Bibliographic record

Venuenpj Clean Air · 2025
Typearticle
Languageen
FieldEnvironmental Science
TopicClimate Change and Health Impacts
Canadian institutionsSimon Fraser UniversityBC Centre for Disease Control
Fundersnot available
KeywordsEnvironmental scienceClimatologyAtmospheric sciencesMeteorologyGeographyGeology

Abstract

fetched live from OpenAlex

Abstract Exposure to fine particulate matter (PM2.5), a primary component of wildfire smoke, and exposure to high temperatures both independently increase the risk of mortality, with evidence of synergistic effects. These environmental stressors often co-occur during wildfire season, and their synergistic effects are expected to worsen with climate change. However, the combined health risks of wildfire-related PM2.5 and temperature remain poorly understood, limiting the effectiveness of public health interventions. This study investigated the joint effects of PM2.5 and temperature on community all-cause mortality across 13 wildfire seasons (2010–2022) in southwest British Columbia, Canada. Daily estimates of ambient PM2.5 and temperature exposure were assigned from a machine learning-based prediction model and satellite data, respectively. Using a case-crossover design and conditional logistic regression, we examined non-linear associations between co-exposures and mortality across deciles and absolute exposure ranges. We found significant, non-linear interactions, with the highest mortality risk observed on days with PM2.5 levels of 12–14 µg/m³ and temperatures ≥ 26 °C (OR = 7.31, 95% CI: [5.34, 10.0]). Co-exposures exceeding the 90th percentile showed synergistic effects, contributing an excess mortality risk of 7.9% (95% CI: 6.1, 9.1). Moderate co-exposure levels posed substantial risks, underscoring the need for greater attention to their public health impacts. Our findings highlight the urgent need to understand and address the compounding effects of PM2.5 and temperature to mitigate risks in a changing climate.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.128

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0020.001
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.274
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2025
Admission routes2
Has abstractyes

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