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Record W4411223905 · doi:10.1093/cercor/bhaf138

The fractal dimension of resting state EEG increases over age in children

2025· article· en· W4411223905 on OpenAlexaff
Si Long Jenny Tou, Tom Chau

Bibliographic record

VenueCerebral Cortex · 2025
Typearticle
Languageen
FieldNeuroscience
TopicEEG and Brain-Computer Interfaces
Canadian institutionsHolland Bloorview Kids Rehabilitation HospitalUniversity of Toronto
Fundersnot available
KeywordsResting state fMRIFractal dimensionElectroencephalographyDimension (graph theory)NeurosciencePsychologyAudiologyFractalMedicineMathematicsMathematical analysisPure mathematics

Abstract

fetched live from OpenAlex

Resting-state electroencephalography (rs-EEG) represents spontaneous neural activity and is increasingly analyzed using nonlinear measures to assess brain complexity. The Higuchi Fractal Dimension (HFD) is a widely used metric for quantifying the fractal properties of EEG signals, yet its developmental trajectory remains largely unexplored. In this study, we examined age-related changes in HFD across childhood, adolescence, and early adulthood. We analyzed eyes-closed rs-EEG from 128 channels in 83 neurotypical participants (8 to 30 yr) from the MIPDB database. To assess developmental patterns, we applied a Gaussian Linear Mixed Model with age, electrode location, and their interaction as predictors, alongside non-parametric cluster-based permutation analysis to evaluate topographical differences. We observed a significant increase in HFD with age (P = 0.001), most pronounced between childhood and adolescence, followed by stabilization in early adulthood. HFD also varied across electrode locations, with higher values in frontal, central, and temporal regions and lower values in parietal and occipital areas. These findings provide new insights into the maturation of neural complexity in rs-EEG, aligning with known structural and functional changes in brain development. This study contributes to the growing body of research on nonlinear EEG dynamics and their relevance to neurodevelopment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.266
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

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