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Vibrio cholerae cystitis following geothermal hot springs exposure in California

2025· article· en· W4411341234 on OpenAlexaff
Gilda Amaral, Christopher F. Lowe, Gordon Ritchie, Conor Broderick, Michael Payne, Aleksandra Stefanovic, Nancy Matic, Nick P.G. Gauthier, Samuel D. Chorlton, Patrick Tang, Marc G. Romney

Bibliographic record

VenueClinical Microbiology Newsletter · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicVibrio bacteria research studies
Canadian institutionsSt. Paul's HospitalKinexus Bioinformatics Corporation (Canada)University of British Columbia
Fundersnot available
KeywordsVibrio choleraeGeothermal gradientMicrobiologyMedicineGeologyBiologyBacteria

Abstract

fetched live from OpenAlex

Vibrio cholerae is a motile, gram-negative bacterium typically found in brackish, coastal waters and most often associated with gastroenteritis. This case details a rare presentation of non-O1/O139 V. cholerae cystitis in an immunocompetent 27-year-old male with no urogenital tract abnormalities following exposure to geothermal hot springs in California. We present the diagnostic considerations and challenges in clinical management for this case, and the relevance of climate change for understanding epidemiology and exposure risk relevant to clinical practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.752
Threshold uncertainty score0.933

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.317
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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