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Record W4411366214 · doi:10.58931/cect.2025.4154

Common Side Effects With Glaucoma Medications

2025· article· en· W4411366214 on OpenAlexaffabout
Evan Michaelov

Bibliographic record

VenueCanadian Eye Care Today · 2025
Typearticle
Languageen
FieldMedicine
TopicGlaucoma and retinal disorders
Canadian institutionsMcGill University
Fundersnot available
KeywordsGlaucomaMedicineSide effect (computer science)OphthalmologyComputer science

Abstract

fetched live from OpenAlex

Glaucoma is a progressive optic neuropathy that affects more than 400 000 Canadians and up to 111 million are expected to be afflicted with the disease worldwide by 2040. Despite trends toward increasing utility of laser and surgical interventions for glaucoma treatment, topical medications remain a mainstay of treatment. These medications often comprise the initial treatment alongside selective laser trabeculoplasty (in open angle subtypes). Additionally, given the progressive nature of glaucoma, many patients who undergo laser or surgery treatments may eventually require the use of topical medications. Although glaucoma drops are generally accepted as safe and low risk for patients, each type carries its own side effect profiles and contraindications. No glaucoma drop is completely benign and can significantly affect patient wellbeing if not selected correctly. Therefore, it is important for ophthalmologists and eye care professionals, who will undoubtedly have numerous glaucoma patients in their care, to be aware of common side effects and contraindications associated with ocular anti-hypertensive agents. This article will outline the side effects and contraindications of the ocular anti-hypertensive agents currently available in Canada.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.020
Threshold uncertainty score0.054

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0160.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.238
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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