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Record W4411395744 · doi:10.1016/j.ekir.2025.06.010

Kidney Disease: Improving Global Outcomes Summit Recommendations on Implementation of Diabetes Management in CKD: From Primary to Data-Driven Collaborative Care

2025· article· en· W4411395744 on OpenAlexaff
Philip Kam‐Tao Li, Michael Cheung, Kai‐Ming Chow, Maria Leung, Lee‐Ling Lim, Juliana Nga Man Lui, Andrea O. Y. Luk, J.-A. Manski-Nankervis, Samuel Seidu, Nikhil Tandon, Adrian Liew, Peter Lin, Fei Chau Pang, Na Tian, Kohjiro Ueki, Martin C. S. Wong, Sophia Zoungas, Kit Man Loo, Kin Lai Chung, Victor Hin-Fai Hung, Vũ Thị Thanh Huyền, Maggie Lee, Junne‐Ming Sung, Cheuk‐Chun Szeto, Man Wo Tsang, Sunny H. Wong, Jack Kit‐Chung Ng, Harriet Chung, Sydney Tang, Kenny Kung, Sing Leung Lui, David Vai Kiong Chao, Coral Cyzewski, Tanya Green, Juliana C.N. Chan

Bibliographic record

VenueKidney International Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicChronic Disease Management Strategies
Canadian institutionsCanadian Heart Research Centre
FundersBoehringer IngelheimAstraZeneca
KeywordsSummitMedicinePrimary careKidney diseaseDiabetes mellitusDisease managementDiseaseIntensive care medicineDiabetes managementFamily medicineType 2 diabetesInternal medicineEndocrinology

Abstract

fetched live from OpenAlex

Type 2 diabetes and chronic kidney disease (CKD) are preventable and treatable. Their silent and progressive clinical course calls for structured assessment with timely feedback to patients and care providers for activating decision-making. Apart from CKD, patients with diabetes can have complications affecting multiple organs, notably the cardiovascular system, eyes, and feet. International practice guidelines recommend annual assessment of the eyes, feet, blood, and urine to detect silent complications and measure cardiovascular-kidney-metabolic (CKM) risk factors to ensure early intervention, including treatment to multiple targets and use of organ-protective drugs. In this report, we highlight the barriers and gaps in the implementation of practice guidelines in managing diabetes in CKD with proposed solutions to overcome such barriers. By improving the practice environment and workflow, nurses can be trained to perform protocol-guided evaluation under medical supervision. The systematic data collection enables physicians to make timely decisions, including drug prescriptions and referrals to other specialists to promote collaborative care, whereas nurses can use the personalized data to empower patient self-management and improve health literacy. This ongoing data collection will form a register to align payers, providers, and patients in delivering data-driven and value-based care with the creation of real-world evidence to verify treatment effectiveness and identify care gaps while providing on-the-job training. When accompanied by a biobank, the ongoing collection and analysis of this multidimensional data will refine diagnosis, classification, prognosis, and treatment in pursuit of precision medicine.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.376
Threshold uncertainty score0.836

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.372
Teacher spread0.352 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

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