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Unveiling Health Security Patterns in the European Union through a Hybrid Entropy-CoCoSo and K-Means Clustering Framework

2025· preprint· en· W4411449293 on OpenAlexaff
Adel A. Nasser, Yahya Ali Al-Samawi, Abed Saif Alghawli, Amani A. K. Essayed

Bibliographic record

VenueF1000Research · 2025
Typepreprint
Languageen
FieldMedicine
TopicViral Infections and Outbreaks Research
Canadian institutionsArtificial Intelligence in Medicine (Canada)
FundersDeanship of Scientific Research, Prince Sattam bin Abdulaziz University
KeywordsOpen peer reviewPlant biologyEuropean unionCluster analysisComputational biologyBiologyPhysiologyMedicineComputer scienceArtificial intelligenceInternational tradeBusinessBotany

Abstract

fetched live from OpenAlex

Objectives: This study aimed to examine health security (HeS) patterns across European Union (EU) member states to address intra-regional disparities in health security, align with EU-wide policy objectives, and propose evidence-based recommendations for harmonizing preparedness measures while respecting national sovereignty. Methods: This research employed a hybrid multi-criteria decision-making framework, combining the Entropy Weight Method and Combined Compromise Solution (CoCoSo), to assess and rank EU countries, drawing on six Global Health Security Index indicators. K-means clustering classified countries into three performance tiers: High, Intermediate, and Dangerous. Data from the GHSI (2019, 2021) and the aggregated 2017-2021 period were analyzed to track temporal trends and cross-regional performance disparities. A comparative analysis of HeS priorities with the African and Eastern Mediterranean (EMR) Regions further contextualized the EU's HeS landscape. Results: Detection and Reporting, and Rapid Response emerged as the most critical dimensions influencing performance, while Risk Environment and Compliance with Norms showed minimal differentiation. High-performing countries, such as Finland and Germany, demonstrated resilience in surveillance and rapid response, while lower-tier nations, Cyprus, Luxembourg, Malta, and Romania, exhibited systemic vulnerabilities in biosecurity and emergency planning. Post-2019, health system resilience gained prominence, while compliance and risk environment remained neglected. The temporal analysis highlighted post-pandemic shifts in health system disparities. Cross-regional comparisons underscoring context-specific challenges. Conclusion: This study highlights the need for targeted investments in surveillance systems, laboratory infrastructure, and crisis preparedness to address specific gaps in different clusters. A metrics-driven framework can reduce regional disparities, promoting equity in preparedness. Policymakers should adopt a collaborative approach to mitigate crises, using high-performing clusters as benchmarks.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmano category
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Simulation or modelinglow
gptno category
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Observationallow
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.481
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0070.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.002
Research integrity0.0000.005
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.407
Teacher spread0.351 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

The models applied no category: nothing in the taxonomy fit this work.

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designSimulation or modeling · Observational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

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