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Unveiling Health Security Patterns in the European Union through a Hybrid Entropy-CoCoSo and K-Means Clustering Framework

2025· preprint· en· W4411449293 on OpenAlexaff
Adel A. Nasser, Yahya Ali Al-Samawi, Abed Saif Alghawli, Amani A. K. Essayed

Bibliographic record

VenueF1000Research · 2025
Typepreprint
Languageen
FieldMedicine
TopicViral Infections and Outbreaks Research
Canadian institutionsArtificial Intelligence in Medicine (Canada)
FundersDeanship of Scientific Research, Prince Sattam bin Abdulaziz University
KeywordsOpen peer reviewPlant biologyEuropean unionCluster analysisComputational biologyBiologyPhysiologyMedicineComputer scienceArtificial intelligenceInternational tradeBusinessBotany

Abstract

fetched live from OpenAlex

Objectives: This study aimed to examine health security (HeS) patterns across European Union (EU) member states to address intra-regional disparities in health security, align with EU-wide policy objectives, and propose evidence-based recommendations for harmonizing preparedness measures while respecting national sovereignty. Methods: This research employed a hybrid multi-criteria decision-making framework, combining the Entropy Weight Method and Combined Compromise Solution (CoCoSo), to assess and rank EU countries, drawing on six Global Health Security Index indicators. K-means clustering classified countries into three performance tiers: High, Intermediate, and Dangerous. Data from the GHSI (2019, 2021) and the aggregated 2017-2021 period were analyzed to track temporal trends and cross-regional performance disparities. A comparative analysis of HeS priorities with the African and Eastern Mediterranean (EMR) Regions further contextualized the EU's HeS landscape. Results: Detection and Reporting, and Rapid Response emerged as the most critical dimensions influencing performance, while Risk Environment and Compliance with Norms showed minimal differentiation. High-performing countries, such as Finland and Germany, demonstrated resilience in surveillance and rapid response, while lower-tier nations, Cyprus, Luxembourg, Malta, and Romania, exhibited systemic vulnerabilities in biosecurity and emergency planning. Post-2019, health system resilience gained prominence, while compliance and risk environment remained neglected. The temporal analysis highlighted post-pandemic shifts in health system disparities. Cross-regional comparisons underscoring context-specific challenges. Conclusion: This study highlights the need for targeted investments in surveillance systems, laboratory infrastructure, and crisis preparedness to address specific gaps in different clusters. A metrics-driven framework can reduce regional disparities, promoting equity in preparedness. Policymakers should adopt a collaborative approach to mitigate crises, using high-performing clusters as benchmarks.

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How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmano category
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Simulation or modelinglow
gptno category
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Observationallow
models splitAgreement compares identical category sets and study designs across arms.

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.013
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.015
Threshold uncertainty score0.044

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.013
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0080.005
Science and technology studies0.0010.002
Scholarly communication0.0040.002
Open science0.0010.003
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.407
Teacher spread0.351 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

The models applied no category: nothing in the taxonomy fit this work.

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designSimulation or modeling · Observational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

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