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Record W4411471974 · doi:10.1371/journal.pdig.0000874

Efficient slice anomaly detection network for 3D brain MRI Volume

2025· article· en· W4411471974 on OpenAlexafffund
Zeduo Zhang, Yalda Mohsenzadeh

Bibliographic record

VenuePLOS Digital Health · 2025
Typearticle
Languageen
FieldComputer Science
TopicAnomaly Detection Techniques and Applications
Canadian institutionsVector InstituteWestern University
FundersVector Institute
KeywordsComputer scienceBenchmark (surveying)Feature (linguistics)Anomaly detectionArtificial intelligencePattern recognition (psychology)Volume (thermodynamics)Convolutional neural networkIdentification (biology)Code (set theory)Data mining

Abstract

fetched live from OpenAlex

Current anomaly detection methods excel with benchmark industrial data but struggle with natural images and medical data due to varying definitions of 'normal' and 'abnormal.' This makes accurate identification of deviations in these fields particularly challenging. Especially for 3D brain MRI data, all the state-of-the-art models are reconstruction-based with 3D convolutional neural networks which are memory-intensive, time-consuming and producing noisy outputs that require further post-processing. We propose a framework called Simple Slice-based Network (SimpleSliceNet), which utilizes a model pre-trained on ImageNet and fine-tuned on a separate MRI dataset as a 2D slice feature extractor to reduce computational cost. We aggregate the extracted features to perform anomaly detection tasks on 3D brain MRI volumes. Our model integrates a conditional normalizing flow to calculate log likelihood of features and employs the contrastive loss to enhance anomaly detection accuracy. The results indicate improved performance, showcasing our model's remarkable adaptability and effectiveness when addressing the challenges exists in brain MRI data. In addition, for the large-scale 3D brain volumes, our model SimpleSliceNet outperforms the state-of-the-art 2D and 3D models in terms of accuracy, memory usage and time consumption. Code is available at: https://github.com/Jarvisarmy/SimpleSliceNet.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.013
Threshold uncertainty score0.026

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.266
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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