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ICU Mortality Prediction Using XGBoost-based Scoring Systems: A Study from a Developing Country

2025· article· en· W4411497162 on OpenAlex
Reema Karasneh, Sayer Al‐Azzam, Karem H. Alzoubi, Mohammad Araydah, Dania Rahhal, Yamin Al-Azzam, Zelal Kharaba, Suad Kabbaha, Mamoon A. Aldeyab

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueReviews on Recent Clinical Trials · 2025
Typearticle
Languageen
FieldMedicine
TopicSepsis Diagnosis and Treatment
Canadian institutionsMcMaster UniversityHamilton Health SciencesImpact
Fundersnot available
KeywordsMedicineReceiver operating characteristicLogistic regressionMachine learningIntensive careRetrospective cohort studyAPACHE IIHealth careArtificial intelligencePopulationPredictive modellingArea under the curveIntensive care medicineEmergency medicineIntensive care unitInternal medicineComputer scienceEnvironmental health

Abstract

fetched live from OpenAlex

BACKGROUND: Accurate mortality prediction in intensive care units (ICUs) is essential for enhancing patient outcomes and optimizing healthcare resource allocation. Traditional scoring systems, such as APACHE, APACHE II, and SAPS, have limitations in handling complex, high- -dimensional ICU data. In this study, multiple machine learning models were compared to establish an efficacious predictive model for mortality tailored explicitly to the Jordanian population and to explicate factors strongly associated with mortality. METHODS: This study was conducted as a single-center, retrospective cohort investigation, and the XGBoost machine learning algorithm was used to develop a novel ICU mortality prediction model. The model aimed to achieve superior prediction accuracy using a diverse set of readily available clinical data, including demographics, comorbidities, laboratory results, and medication groups. Model performance was evaluated against alternative machine learning algorithms, including logistic regression, conventionally employed in traditional scoring systems. RESULTS: Comparative analysis revealed that the XGBoost model performed better than other scoring systems, manifesting heightened accuracy (87.91%), sensitivity (92.88%), and Area Under the Receiver-Operating Characteristic Curve (AUC-ROC) Score/Curve (94.29%). Notably, the patient's length of hospital stays, albumin levels, and urea levels emerged as the most substantial predictors for ICU mortality, each exhibiting respective SHAP values of 0.5, 0.41, and 0.37. CONCLUSION: A locally adapted ICU mortality prediction model was developed, underscoring the pivotal role of predictors such as hospital stay duration, albumin, and urea levels in predicting patient outcomes. The heightened accuracy and sensitivity of the XGBoost model signify its potential as an invaluable tool in the critical task of mortality prediction within the Jordanian ICU context.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmano category
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Observationalhigh
gptno category
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Simulation or modelinglow
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.017
metaresearch head score (Gemma)0.019
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.265
Threshold uncertainty score0.989

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0170.019
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.827
GPT teacher head0.635
Teacher spread0.192 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it