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Record W4411585057 · doi:10.1371/journal.pone.0326339

Diagnosis of knee meniscal injuries using artificial intelligence: A systematic review and meta-analysis of diagnostic performance

2025· review· en· W4411585057 on OpenAlexaff
Soheil Mohammadi, Ali Jahanshahi, Mohammad Shahrabi Farahani, Mohammad Amin Salehi, Negin Frounchi, Ali Guermazi

Bibliographic record

VenuePLoS ONE · 2025
Typereview
Languageen
FieldMedicine
TopicKnee injuries and reconstruction techniques
Canadian institutionsMcGill University Health Centre
Fundersnot available
KeywordsMeta-analysisMedicineComputer sciencePathology

Abstract

fetched live from OpenAlex

AIM OF THE STUDY: The aim was to systematically review the literature and perform a meta-analysis to estimate the performance of artificial intelligence (AI) algorithms in detecting meniscal injuries. MATERIALS AND METHODS: A systematic search was performed in the Scopus, PubMed, EBSCO, Cinahl, Web of Science, IEEE Xplore, and Cochrane Central databases on July, 2024. The included studies' reporting quality and risk of bias were evaluated using the Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD) and the Prediction Model Study Risk of Bias Assessment Tool (PROBAST), respectively. Also, a meta-analysis was done using contingency tables to estimate diagnostic performance metrics (sensitivity and specificity), and a meta-regression analysis was performed to investigate the effect of the following variables on the main outcome: imaging view, data augmentation and transfer learning usage, and presence of meniscal tear in the injury, with a corresponding 95% confidence interval (CI) and a P-value of 0.05 as a threshold for significance. RESULTS: Among 28 included studies, 92 contingency tables were extracted from 15 studies. The reference standard of the studies were mostly expert radiologists, orthopedics, or surgical reports. The pooled sensitivity and specificity for AI algorithms on internal validation were 81% (95% CI: 78, 85), and 78% (95% CI: 72, 83), and for clinicians on internal validation were 85% (95% CI: 76, 91), and 88% (95% CI: 83, 92), respectively. The pooled sensitivity and specificity for studies validating algorithms with an external test set were 82% (95% CI: 74, 88), and 88% (95% CI: 84, 91), respectively. CONCLUSION: The results of this study imply the lower diagnostic performance of AI-based algorithms in knee meniscal injuries compared with clinicians.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.023
metaresearch head score (Gemma)0.066
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.023
Threshold uncertainty score0.120

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0230.066
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0210.037
Bibliometrics0.0110.009
Science and technology studies0.0010.001
Scholarly communication0.0040.002
Open science0.0030.002
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.166
GPT teacher head0.370
Teacher spread0.204 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

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