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Record W4411597645 · doi:10.1002/mrm.30616

MRI for biology‐guided radiation therapy: Are we there yet? A summary of the 2024 ISMRM member‐initiated session

2025· review· en· W4411597645 on OpenAlexaff
Sirisha Tadimalla, Jie Deng, Peter B. Barker, Hyunsuk Shim, Stefan A. Reinsberg, Chenyang Liu, Jing Cai, Jonathan Goodwin, Leith Rankine, Yufeng Wang, Petra J. van Houdt, Ralph P. Mason, Zhaoyang Fan

Bibliographic record

VenueMagnetic Resonance in Medicine · 2025
Typereview
Languageen
FieldMedicine
TopicAdvanced MRI Techniques and Applications
Canadian institutionsUniversity of British Columbia
FundersNational Institute of Biomedical Imaging and BioengineeringNational Cancer InstituteNational Institutes of HealthUniversity of SydneyCancer Institute NSWCancer Prevention and Research Institute of Texas
KeywordsSession (web analytics)Context (archaeology)Medical physicsClinical PracticeAdaptation (eye)MedicineComputer sciencePsychologyNeuroscienceBiologyPhysical therapy

Abstract

fetched live from OpenAlex

Abstract At the 2024 ISMRM Annual Meeting in Singapore, a member‐initiated session on MRI for biology‐guided radiation therapy (RT), endorsed by the ISMRM MR in RT Study Group, was successfully organized. The session convened a diverse group of global experts in quantitative MRI for RT, who presented the latest research on the technical development and clinical translation of various quantitative MRI techniques for biology‐guided RT planning and delivery. The session highlighted clinical needs and a variety of MRI techniques, including MR spectroscopic imaging, oxygen‐enhanced MRI, four‐dimensional MR fingerprinting, dynamic contrast‐enhanced MRI, and 129 Xe MRI. Additionally, technical aspects and challenges for clinical translation of quantitative MRI into biology‐guided RT were presented, both in the context of RT planning and adaptation. This article summarizes the progress made in this emerging field, identifies key challenges that need to be addressed, and outlines areas for future research. These insights are crucial for the integration of quantitative MRI techniques into RT clinical practice, ultimately aiming to improve patient outcomes through more personalized RT approaches.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.007
Threshold uncertainty score0.022

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0070.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.100
GPT teacher head0.432
Teacher spread0.332 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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