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Record W4411614489 · doi:10.3389/fpubh.2025.1603627

The role of physical activity in preventing cognitive decline among U.S. older adults with diabetes and prediabetes: a cross-sectional study

2025· article· en· W4411614489 on OpenAlexaff
Yifei Wang, Dezheng Liu, Hongli Wang, Mengzhao Wang, Weiqi Ruan, Yanbai Han

Bibliographic record

VenueFrontiers in Public Health · 2025
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsUniversity of Alberta
FundersDivision of Graduate EducationNational Social Science Fund of China
KeywordsPrediabetesNational Health and Nutrition Examination SurveyMedicineCross-sectional studyDigit symbol substitution testCognitionDiabetes mellitusGerontologyConfoundingCognitive declineLogistic regressionVerbal fluency testType 2 diabetesTrail Making TestDemographyPhysical therapyInternal medicineDementiaDiseaseNeuropsychologyEndocrinologyEnvironmental healthPopulationPsychiatryPathology

Abstract

fetched live from OpenAlex

Background: Physical activity (PA) has been widely recognized as a key strategy to slow age-related cognitive decline. However, its specific effects on older adults with diabetes or prediabetes remain poorly understood. Therefore, we investigated the association between different levels of PA and cognitive function among older Americans with diabetes and prediabetes. Methods: This cross-sectional study used data from the 2011-2014 National Health and Nutrition Examination Survey (NHANES) and included a total of 1,299 older adults aged ≥60 years. The PA levels were determined by calculating the weekly metabolic equivalent of task time (MET-min/week). The participants' cognitive abilities were assessed using the Consortium to Establish a Registry for Alzheimer's disease (CERAD) Word Learning Test, Animal Fluency Test (AFT), and Digit Symbol Substitution Test (DSST). Multivariable logistic regression models were used to analyze the association between different PA levels and cognitive function in patients with diabetes and prediabetes. The study utilized the restricted cubic spline (RCS) models to explore the nonlinear correlation of PA with cognitive function. Results: = 0.039). According to the RCS models, PA showed a significant nonlinear correlation with cognitive function, and the risk of cognitive decline decreased with the increase of PA levels. Conclusion: In older adults with diabetes and prediabetes, moderate and high levels of physical activity are associated with a lower risk of cognitive decline. Clinicians should encourage patients to participate actively in exercise to maximize the benefits of PA.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.013
Threshold uncertainty score0.025

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.326
Teacher spread0.315 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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