Bibliographic record
Abstract
Canada’s Drug Agency (CDA-AMC) recommends that Jemperli in combination with carboplatin-paclitaxel be reimbursed for the treatment of adults with primary advanced or first recurrent endometrial cancer who are candidates for systemic therapy, if certain conditions are met. Jemperli in combination with carboplatin-paclitaxel should only be covered to treat adult patients who have primary stage III or IV endometrial cancer, experienced a first disease recurrence and have not previously received systemic anticancer therapy for advanced disease, received previous systemic anticancer therapies before (neoadjuvant) or after (adjuvant) surgical removal of the tumour and experienced a first recurrence of disease at least 6 months after the completion of adjuvant or neoadjuvant treatment, and are in relatively good health (as measured by performance status). Jemperli should only be reimbursed in combination with carboplatin-paclitaxel if prescribed by clinicians with expertise in advanced endometrial cancer. Treatment should be supervised and administered in institutions with expertise in systemic therapy delivery. The cost of Jemperli should be reduced.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".