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Record W4411641098 · doi:10.1097/id9.0000000000000172

Chronic schistosomiasis and strongyloidiasis mimicking irritable bowel syndrome over multiple decades: A case report

2025· article· en· W4411641098 on OpenAlexaff
Jonathan D. Cook, Kara Grace Hounsell, Candice Madakadze, Ranie Ahmed, Andrea K. Boggild

Bibliographic record

VenueInfectious Diseases & Immunity · 2025
Typearticle
Languageen
FieldImmunology and Microbiology
TopicParasites and Host Interactions
Canadian institutionsUniversity Health NetworkToronto General HospitalUniversity of Toronto
Fundersnot available
KeywordsIrritable bowel syndromeSchistosomiasisStrongyloidiasisMedicineHelminthiasisGastroenterologyHelminthsImmunology

Abstract

fetched live from OpenAlex

spp. can present with longstanding gastrointestinal symptoms that mimic irritable bowel syndrome (IBS). In this case report, we describe a patient who was misdiagnosed with IBS for several decades before receiving a definitive diagnosis of chronic helminthiasis. Treatment with first-line antihelminthics resulted in complete and sustained resolution of symptoms. We review the life cycle, epidemiology, clinical presentations, diagnosis, and management of chronic helminthiases in the context of IBS. We further discuss the impact of misdiagnosis on both the patient and the healthcare system. Given the significant individual and economic burdens of IBS and the diagnostic uncertainty associated with low sensitivity of standard diagnostic tests for helminth infections, healthcare professionals should maintain a low threshold for testing and empiric treatment in patients with relevant travel and medical history.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.109
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.279
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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