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Record W4411668162 · doi:10.1093/ehjdh/ztaf061

The hope and the hype of artificial intelligence for syncope management

2025· article· en· W4411668162 on OpenAlex
Samuel L. Johnston, Ercole John Barsotti, Konstantinos Bakogiannis, Artur Fedorowski, Fabrizio Ricci, Eric G Heller, Robert S. Sheldon, Richard Sutton, Win‐Kuang Shen, Venkatesh Thiruganasambandamoorthy, Mehul Adhaduk, William H. Parker, Arwa Aburizik, Corey R Haselton, Alex J Cuskey, Sangil Lee, Madeleine Johansson, Donald E. Macfarlane, Paari Dominic, Haruhiko Abe, B. Hygriv Rao, Avinash Mudireddy, Milan Sonka, Roopinder K. Sandhu, Rose Anne Kenny, Giselle M. Statz, Rakesh Gopinathannair, David G. Benditt, Franca Dipaola, Mauro Gatti, Roberto Menè, Alessandro Giaj Levra, Dana Shiffer, Giorgio Costantino, Raffaello Furlan, Martin H. Ruwald, Vassilios Vassilikos, Milena A. Gebska, Brian Olshansky

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueEuropean Heart Journal - Digital Health · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiovascular Syncope and Autonomic Disorders
Canadian institutionsUniversity of OttawaLibin Cardiovascular Institute of AlbertaOttawa Public HealthUniversity of Calgary
Fundersnot available
KeywordsSyncope (phonology)BusinessPsychologyMedicineCardiology

Abstract

fetched live from OpenAlex

Aims: Syncope remains a diagnostic challenge despite advancements in testing and treatment. Cardiac syncope is an independent predictor of mortality and can be difficult to distinguish from other causes of transient loss of consciousness (TLOC). This paper explores whether artificial intelligence (AI) can improve the evaluation and management of patients with syncope. Methods and results: We conducted a literature review and incorporated the opinions of experts in the fields of syncope and AI. The cause of TLOC is often unclear, hospitalization criteria are ambiguous, diagnostic tests are frequently non-informative, and assessments are costly. Patients are left with unanswered questions and limited guidance. Artificial intelligence (AI) has the potential to optimize syncope evaluation by processing large data sets, detecting imperceptible patterns, and assisting clinicians. However, AI has limitations, including errors, lack of human empathy, and uncertain clinical utility. Liability issues further complicate its integration. We present three viewpoints: (i) AI is crucial for advancing syncope management; (ii) AI can enhance the patient experience; and (iii) AI in syncope care is inevitable. Conclusion: Artificial intelligence may improve syncope diagnosis and management, particularly through machine learning-based test interpretation and wearable device data. However, it has yet to surpass human clinical judgment in complex decision-making. Current challenges include gaps in understanding syncope mechanisms, AI interpretability, generalizability, and clinical integration. Standardized diagnostic approaches, real-world validation, and curated data sets are essential for progress. Artificial intelligence may enhance efficiency and communication but raises concerns regarding confidentiality, bias, inequities, and legal implications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.977
Threshold uncertainty score0.287

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.314
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it