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Record W4411738651 · doi:10.3389/fragi.2025.1532550

Possibility of screening for mild cognitive impairment via an eye tracking-based cognitive scale

2025· article· en· W4411738651 on OpenAlexaboutno aff
Naoki Kodama, Sou Takahashi, Yuji Kawase, Satoshi Naruse, Katsuya Urakami

Bibliographic record

VenueFrontiers in Aging · 2025
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsnot available
Fundersnot available
KeywordsMontreal Cognitive AssessmentCognitionCognitive impairmentCognitive evaluation theoryPsychologyAudiologyCorrelationVirtual realityMedicinePsychiatryComputer scienceArtificial intelligence

Abstract

fetched live from OpenAlex

Introduction: The Montreal Cognitive Assessment (MoCA) is widely used as a screening test for mild cognitive impairment (MCI). However, the MoCA takes approximately 15 min to administer and evaluate by skilled examiners, such as medical professionals. This study assessed whether an eye tracking-based cognitive scale using virtual reality (VR) was accurate and efficient to screen for MCI. Methods: This study included 143 patients. The Virtual Reality-Based Cognitive Function Examination (VR-E) was used with all participants to evaluate their memory, judgment, spatial cognition, calculation, and language function. Results: Significant differences were observed in all cognitive domains of memory, judgment, spatial cognition, calculation, and language function between the Alzheimer's disease (AD), MCI, and older healthy control (HC) groups. The area under the curve value of the VR-E score for the HC and MCI groups was 0.857, and that for the AD and MCI groups was 0.870. The correlation coefficient between the MMSE and VR-E scores was 0.566 (p < 0.001), and that between the Japanese version of the MoCA (MoCA-J) and VR-E scores was 0.648 (p < 0.001), which indicated a moderate correlation in both comparisons. Conclusion: The VR-E had the same diagnostic performance results as the MoCA-J, thus the VR-E has potential for use in screening patients for MCI.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.360
Teacher spread0.339 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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